Gene Therapy Viral Vectors: Advances and Challenges

GUEST EDITOR

Prof. Axel Schambach, Hannover Medical School, Germany

As cell and gene therapies move towards the clinic, critical developments in the production of viral vectors are required to enable large-scale manufacturing and distribution. A balanced overview of the merits and challenges of the different viral vector types is provided; complemented by a discussion of the key manufacturing considerations to enable large-scale, quality-assured vectors for clinical use including culture systems and their impact on vector productivity.