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Cell & Gene Therapy Insights

Cell & Gene Therapy Insights

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Pros and cons of suspension culture systems in LVV upstream bioprocessing

Nolan Sutherland


VECTOR CHANNEL: SUSPENSION CULTURE SYSTEMS


Nolan Sutherland graduated from the University of Massachusetts, Amherst with a BS in Biochemistry and Molecular Biology where his research areas of focus were on molecular cloning and RNAi. Over the past 10 years he has worked in both Upstream and Downstream Process Development roles, getting his start in the area of enzyme replacement therapies before being hired into the Vector PD team at bluebird bio. Since that time, the majority of Nolan’s work has been on developing suspension-based lentiviral vector production systems for commercial manufacturing. His areas of focus include process development, optimization and improvement at the miniature and bench-scales, nanoparticle analysis and characterization, as well as scale-up and tech transfer. Nolan lives with his dog and future wife on the south shore of the Boston area. He enjoys cycling, traveling, and brewing beer to share with his fellow “Brewbirds” clubmates at their Cambridge nest.

DOI: 10.18609/cgti.2019.091
Citation: Cell & Gene Therapy Insights 2019; 5(Suppl. 5), 925-930.
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