Same-section spatial multiomics: a platform for detailed analysis of the solid TME
Sponsor
As I-O therapy developers work to recreate the successes seen in blood cancers for solid tumor applications, the tumor microenvironment (TME) represents a crucial barrier to understand and overcome. The TME plays a key role in cancer development and behavior, and analysis can become increasingly difficult with tumor progression.
Spatial biology represents an exciting approach to better understand the TME – but the primary limitation of current spatial technologies lies in their inability to simultaneously capture protein and RNA information within the same histological section.
This webinar presents the same-section spatial multiomic capabilities of the MACSima® Platform, which allows for the detection of hundreds of proteins and dozens of RNAs in an easy and automated manner. Simultaneous RNA detection is now possible through RNAsky™, a newly developed assay designed to target virtually any RNA of interest with high sensitivity and specificity. Utilizing MACS® iQ View Analysis Software, we identified the present cell populations and quantified their expression profiles, demonstrating how spatially-resolved multiomics data can be used to characterize the heterogeneity of solid tumor TMEs.
Attend this webinar to learn about:
- A same-section spatial multiomics assay and its advantages for protein and RNA analysis
- The applications of same-section spatial RNA and protein detection within I-O
- A new assay for automated spatial gene expression analysis specifically within the solid tumor TME
SPEAKERS
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