Harnessing flow cytometry for high-throughput screening in immunotherapy development

Kevin Z. Chen holds a Master of Science in Cancer Biology from Emory University. As a Scientist in the Translational Sciences Department - Biomarkers and Bioanalysis Group at Arcellx, he specializes in utilizing spectral and conventional flow cytometry platforms to evaluate clinical biomarkers of patient response both pre- and post-CAR-T infusion. Kevin leads the development and validation of multiparameter flow cytometry assays, employing over 25 fluorochromes to comprehensively characterize T cell phenotype and function. He also serves as a device manager for the BD FACS Lyric and Cytek Aurora 5-laser Cytometers. Kevin's research has contributed to the understanding of T cell immunotherapy, particularly in enhancing CAR-T cell manufacturing processes.

Jonah Riddell, PhD is a Product Manager supporting the iQue® HTS by Cytometry Platform at Sartorius Corporation. He is both an accomplished benchtop scientist and commercial leader in immunology with over 25 years of experience. Integrating a deep understanding of immunology with strategic market planning and cross-functional team leadership he is looking to innovate new products to aid in clinical and pre-clinical research. Jonah has been associated with esteemed institutions such as the Harvard Stem Cell Institute, Boston Childrens Hospital, Roswell Park Cancer Institute, Cell Signaling Technology, Advanced Instruments, Bio-Techne where his experience spans from academic to biopharma to clinical testing.

As the Director of Flow Cytometry at AstraZeneca, I lead a global team operating in Washington DC, Cambridge and Boston. We support the work of over 600 scientists and 150 projects each year, supporting the discovery and development of new therapies for various diseases. With an education in biotechnology and over 15 years of experience in flow cytometry, immunology, virology, and data science, I have a strong background in both human and non-human primate animal models, neuroscience, and cell therapy.