Taking a high-throughput approach to enhancing the target specificity and stability of nanoparticles

David McCall, Senior Editor, BioInsights, speaks to Genentech’s Chun-Wan Yen, Senior Principal Scientist, and Yuchen Fan, Principal Scientist, about current and future innovations in nucleic acid formulation and delivery utilizing nanoparticles. They explore challenges and advances in achieving targeted extrahepatic delivery of nucleic acids in vivo, and discuss the application of high-throughput screening and AI/ML tools to extend the capabilities and reach of LNP-based drug delivery.

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