Tackling the key challenges for therapeutic oligonucleotide manufacture: cost, scale, and sustainability

Nucleic Acid Insights 2024; 1(9), 325–332

DOI: 10.18609/nai.2024.041

Published: 26 November
Interview
Ben Andrews


In this wide-ranging interview David McCall, Senior Editor, BioInsights, and Ben Andrews, Senior Manager in Strategic External Development, GlaxoSmithKline, discuss the key challenges and opportunities for successful oligonucleotide manufacturing at scale, the merits and drawbacks of various synthesis options, and current efforts to mitigate the industry’s environmental impact.