Precise mRNA purity assessment for accelerated therapeutic development and release testing

Thursday 08:00 PDT / 11:00 EDT / 16:00 BST / 17:00 CEST

Sponsor

Precise mRNA purity assessment for accelerated therapeutic development and release testing

The quantification of mRNA in solutions presents an array of challenges, including a lack of accuracy when determining purity ratio with traditional technologies, and the introduction of potential errors and risks through sample preparation or dilution.

Attend this webinar to learn about precise mRNA purity assessment that provides results that closely match theoretical purity ratios while avoiding risks associated with sample dilution. Methods to enhance the efficiency of mRNA production via the application of at-line process analytical technology (PAT), which can drive rapid in-process responses and enable real-time control, will also be discussed.

Attend this webinar for insights into:

Limitations of traditional methods for quantifying mRNA
A comparison of study results using process analytical techniques with traditional fixed-pathlength spectroscopy
How boosting the accuracy and reliability of mRNA analysis facilitates faster therapeutic development and efficient release testing through enhanced process control

Paul Mania

Bioanalytics Applications Specialist at Repligen

Paul Mania, B.Sc., CTech Bioanalytics Applications Specialist, is a seasoned professional who has been with Repligen since 2017. With a solid foundation in Biological Science earned from Duquesne University and substantial industry experience as a laboratory technician, Paul brings a wealth of knowledge to his role.

In his capacity as a Bioanalytics Applications Specialist, Paul is dedicated to ensuring our customers' success. He specializes in method validation and implementation, working tirelessly to seamlessly integrate our customer solutions and expedite their functionality. His mission is to optimize his customer’s applications, harnessing the power of at-line concentration measurement and the remarkable precision of variable pathlength spectroscopy to the fullest.

Joe Ferraiolo

Director, Bioanalytical Applications at Repligen

Joe Ferraiolo leads the Repligen Bioanalytics Applications Team, overseeing the variable pathlength spectroscopy solutions for in-line and at-line applications. Drawing from over a decade of hands-on experience in analytical applications, Joe plays a pivotal role in enhancing our customers' success. Joe's leadership ensures successful validations, smooth method development, and the integration of highly accurate process analytical tools into their biologic platforms, addressing critical production stages and bolstering their capabilities in biotechnology.

in 3

Days

SPEAKERS

Paul Mania

Bioanalytics Applications Specialist at Repligen

Joe Ferraiolo

Director, Bioanalytical Applications at Repligen