Protein characterization using variable pathlength spectroscopy: high- & low-concentration methods
Vaccine Insights 2023; 2(11), 447–455
DOI: 10.18609/vac/2023.60
Published: 5 January
Innovator Insight
The potential to tailor bioanalytical methods to specific biologic therapeutic products is critical to effectively meet regulatory CMC expectations. This article describes the use of variable pathlength technology for protein concentration measurement, with a particular focus on exploring low- and high-concentration methodologies.