BioInsights - Vol 6 Issue 10

CELL & GENE THERAPY INSIGHTS

November 2020 Issue

Vol 6 Issue 10

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Featuring

Issue Spotlight: Cell therapy bioprocessing and analytics: today’s key tools and innovation requirements to meet future demand
Focus: Critical raw and ancillary materials
Focus: Adherent culture systems 2020
Other articles
Webinars

SPOTLIGHT

Cell therapy bioprocessing and analytics: today’s key tools and innovation requirements to meet future demand
John Paul Tomtishen III
Guest Editor:
John Paul Tomtishen III, Director of Manufacturing, Technical Operations at Legend Biotech Co.
Co-sponsor

Foreword

Cell therapy bioprocessing and analytics: today’s key tools and innovation requirements to meet future demand

Cell therapy bioprocessing and analytics: today’s key tools and innovation requirements to meet future demand

John Paul Tomtishen III
1 December 2020
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Editorial

Process development: how to win the race in cell & gene therapy

Process development: how to win the race in cell & gene therapy

4 November 2020
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Expert Insight

Measurement: the central nervous system of a quality manufacturing line for tissue engineering and regenerative medicine products

Measurement: the central nervous system of a quality manufacturing line for tissue engineering and regenerative medicine products

M McCorry, R Robinson-Zeigler, R McFarland et al.
25 November 2020
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The role of flow cytometry in advanced therapy medicinal products

The role of flow cytometry in advanced therapy medicinal products

Theo Nastos, PhD
20 November 2020
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Limiting variability to achieve reproducibility in cell manufacturing

Limiting variability to achieve reproducibility in cell manufacturing

Anne Lamontagne, Andrew Fesnak
11 November 2020
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Innovator Insight

De-risking the final formulation, fill and finish step in cell therapy manufacturing: considerations for an automated solution

De-risking the final formulation, fill and finish step in cell therapy manufacturing: considerations for an automated solution

Dalip Sethi, Annie Cunningham
26 November 2020
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Interview

Addressing pain points in iPSC-derived cell therapy manufacture and scale-up

Addressing pain points in iPSC-derived cell therapy manufacture and scale-up

Bruno Marques, PhD
24 November 2020
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Industrializing allogeneic cell therapy bioprocessing: devising streamlined solutions to complex challenges

Industrializing allogeneic cell therapy bioprocessing: devising streamlined solutions to complex challenges

Lior Raviv
23 November 2020
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γδ T cell therapy: devising a manufacturing-friendly bioprocess

γδ T cell therapy: devising a manufacturing-friendly bioprocess

Dr Sean O’Farrell
17 November 2020
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Challenges & trends in stem cell-derived extracellular vesicle bioprocessing

Challenges & trends in stem cell-derived extracellular vesicle bioprocessing

Jorge L Escobar Ivirico
12 November 2020
Read

Expert Roundtable Video

Streamlining and optimizing viral vector bioprocess and analytical development

Streamlining and optimizing viral vector bioprocess and analytical development

J Tarnowski, N Kotsopoulou, K Patel et al.
22 December 2020
Watch

Expert Roundtable

Streamlining and optimizing viral vector bioprocess and analytical development

Streamlining and optimizing viral vector bioprocess and analytical development

19 January 2021
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Methodology Paper

A cell therapy media fill protocol for validation of aseptic processing of cord blood

A cell therapy media fill protocol for validation of aseptic processing of cord blood

F DeDino, K Vincent, D DiNello et al.
24 November 2020
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On Demand Webinar

Abbreviated in-house qualification of real time mycoplasma detection kit

Abbreviated in-house qualification of real time mycoplasma detection kit

Sowmya Viswanathan, PhD
7 January 2021
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Celyad Oncology’s case study: validation approach for accelerated mycoplasma testing

Celyad Oncology’s case study: validation approach for accelerated mycoplasma testing

Dr Sarah Snykers
7 January 2021
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Webinars on Demand: Expert Commentary

Celyad Oncology’s case study: validation approach for accelerated mycoplasma testing

Celyad Oncology’s case study: validation approach for accelerated mycoplasma testing

16 February 2021
Read

Supply Chain FOCUS

Critical raw and ancillary materials

Editorial

How to standardize quality requirements of raw materials

How to standardize quality requirements of raw materials

Bernd Leistler
1 December 2020
Read

Vectors FOCUS

Adherent culture systems 2020

Podcast

Viral vector manufacturing and transfection efficiency in the iCELLis<sup>®</sup> Bioreactor System

Viral vector manufacturing and transfection efficiency in the iCELLis® Bioreactor System

R Leggmann, F Collard, A Nyamay’Antu
17 December 2020
Listen

Interview

Viral vector manufacturing and transfection efficiency in the iCELLis<sup>®</sup> Bioreactor system

Viral vector manufacturing and transfection efficiency in the iCELLis® Bioreactor system

17 December 2020
Read

Editorial

Adherent systems for viral vector production

Adherent systems for viral vector production

Hemant Dhamne, PhD
18 December 2020
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Journal articles

Expert Insight

Improving therapeutic potential of non-viral minimized DNA vectors

Improving therapeutic potential of non-viral minimized DNA vectors

L Arévalo-Soliz, C Hardee, J Fogg et al.
19 November 2020
Read

Commentary

Monoclonal antibodies to enable therapeutic tolerance to stem cell derived transplants?

Monoclonal antibodies to enable therapeutic tolerance to stem cell derived transplants?

Herman Waldmann
23 October 2020
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Interview

Developing a risk mitigation plan for gene therapy manufacturing

Developing a risk mitigation plan for gene therapy manufacturing

J Moscariello, C Davies, M Brewer et al.
9 November 2020
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Multi-modal cell and gene therapy facilities: futureproofing with flexible design

Multi-modal cell and gene therapy facilities: futureproofing with flexible design

Emily Thompson
6 November 2020
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Advancing embryonic stem cell-based therapy in eye disease

Advancing embryonic stem cell-based therapy in eye disease

Jane Lebkowski
19 November 2020
Read

Podcast

Developing a risk mitigation plan for gene therapy manufacturing - Podcast

Developing a risk mitigation plan for gene therapy manufacturing - Podcast

J Moscariello, C Davies, M Brewer et al.
9 November 2020
Listen

FastFacts

GMP compliant residual PEIpro® test: one step closer to commercialization

GMP compliant residual PEIpro® test: one step closer to commercialization

Malik Hellal
3 November 2020
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Managing donor collections during the COVID-19 pandemic

Managing donor collections during the COVID-19 pandemic

Joy Aho
4 November 2020
Read

Webinars