BioInsights - Webinars

CELL & GENE THERAPY INSIGHTS

Upcoming webinars

How to secure and standardize your cell expansion

How to secure and standardize your cell expansion

Anette Brass, Paula Villaescusa Sánchez
6 December 2022
in 5
Days
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The CAR toolkit: progress and challenges in CAR T/NK cell R&D and manufacture

The CAR toolkit: progress and challenges in CAR T/NK cell R&D and manufacture

H Dhamne, T Manning, S Steiner
7 December 2022
in 6
Days
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Enhancing non-viral genome editing, processing, and expansion of T and NK cells

Enhancing non-viral genome editing, processing, and expansion of T and NK cells

Sung Lee
8 December 2022
in 7
Days
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GMP-compliant manufacturing in a closed-system automated bioreactor with a novel cell culture medium

GMP-compliant manufacturing in a closed-system automated bioreactor with a novel cell culture medium

Gonçalo Regalo, Francesco Vitrani
13 December 2022
in 12
Days
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Optimizing HEK293 media for improved titers and VG/Capsid ratios

Optimizing HEK293 media for improved titers and VG/Capsid ratios

Hamid Soleymani
14 December 2022
in 13
Days
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Sustainable plasmid DNA strategies: achieving streamlined, secured supply to clinic and commercialization

Sustainable plasmid DNA strategies: achieving streamlined, secured supply to clinic and commercialization

Andrew Frazer
12 January 2023
in 42
Days
Register

On demand webinars

Extracellular Vesicles: From Waste EVictees to Therapeutic Reality

Extracellular Vesicles: From Waste EVictees to Therapeutic Reality

Amy Kauffman
30 November 2022
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Simplifying lentiviral downstream processing with a novel affinity resin and robust analytical tools

Simplifying lentiviral downstream processing with a novel affinity resin and robust analytical tools

Chantelle Gaskin, Suzy Brown
29 November 2022
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Let the cells thrive - The next generation of cell expansion

Let the cells thrive - The next generation of cell expansion

H Fabre, M Barbisin, M Knaub
22 November 2022
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Scalable AAV production in single use bioreactors

Scalable AAV production in single use bioreactors

Jon Zmuda
21 November 2022
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Industrialization of cell and gene therapies: process development best practices for commercialization readiness

Industrialization of cell and gene therapies: process development best practices for commercialization readiness

Behnam Baghbaderani
17 November 2022
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Improved lentivirus recovery by weak anion exchange capture

Improved lentivirus recovery by weak anion exchange capture

Lisa Marx, PhD
15 November 2022
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Viral vector manufacturing process - addressing bottlenecks with innovative solutions

Viral vector manufacturing process - addressing bottlenecks with innovative solutions

Rachel Legmann
8 November 2022
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How are cationic lipids offering new possibilities in the delivery of RNA therapeutics?

How are cationic lipids offering new possibilities in the delivery of RNA therapeutics?

Malik Hellal, Maria Nicla Loviglio
3 November 2022
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Navigating scalability and consistency in the allogeneic supply chain

Navigating scalability and consistency in the allogeneic supply chain

Anne Dircks, Dean Lee
1 November 2022
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Tailoring viral vector transgene optimization for enhanced efficacy

Tailoring viral vector transgene optimization for enhanced efficacy

Harrison Brown
27 October 2022
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Modulation of both tumor and T cell apoptosis to enhance CART immunotherapy

Modulation of both tumor and T cell apoptosis to enhance CART immunotherapy

Marco Ruella
26 October 2022
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Lentiviral titer determination: Rapid and robust molecular methods suitable for validation

Lentiviral titer determination: Rapid and robust molecular methods suitable for validation

Unnati Dev
25 October 2022
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Regulatory requirements and product attributes for cGMP viral vector production

Regulatory requirements and product attributes for cGMP viral vector production

Shikha Mishra
20 October 2022
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Circulating tumor DNA as a predictive biomarker for immunotherapy response: from clinical trials to clinical practice

Circulating tumor DNA as a predictive biomarker for immunotherapy response: from clinical trials to clinical practice

M Krainock, A Tan, J Simmons
19 October 2022
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Manufacturing GMP-compliant iPSCs in closed and open systems

Manufacturing GMP-compliant iPSCs in closed and open systems

Dr. Dhruv Sareen, Dr. Chao Sheng
18 October 2022
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Scalable suspension lentiviral vector production platforms for cGMP manufacturing

Scalable suspension lentiviral vector production platforms for cGMP manufacturing

Suparna Sanyal, PhD
13 October 2022
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Predicting patient response to immune targeted therapies via interrogation of the TME

Predicting patient response to immune targeted therapies via interrogation of the TME

Dr Caroline Fong
12 October 2022
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The next generation of GMP cell sorting - high-throughput, sterile, scalable

The next generation of GMP cell sorting - high-throughput, sterile, scalable

Samson Rogers, PhD
11 October 2022
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Process development optimization for GMP manufacturing: A CAR-T case study

Process development optimization for GMP manufacturing: A CAR-T case study

Gary Pigeau, PhD
6 October 2022
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Automating HSC gene engineering in a functionally closed system

Automating HSC gene engineering in a functionally closed system

L Stamm, K Krämer, E Papanikolaou
4 October 2022
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Feeder free expansion and closed wash and concentration of a clinically relevant number of human NK cells

Feeder free expansion and closed wash and concentration of a clinically relevant number of human NK cells

Erica Heipertz, PhD
29 September 2022
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Process and analytical insights for GMP manufacturing of mRNA lipid nanoparticles

Process and analytical insights for GMP manufacturing of mRNA lipid nanoparticles

E Cameau, P Zhang, S Ip et al.
28 September 2022
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Manufacturing of NK cells for the clinic: the Spanish experience

Manufacturing of NK cells for the clinic: the Spanish experience

Antonio Perez-Martinez
27 September 2022
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Overcoming contamination risks in cell and gene therapy with aseptic GMP process design using isolator technology

Overcoming contamination risks in cell and gene therapy with aseptic GMP process design using isolator technology

Chris Berridge, Donald Singer
22 September 2022
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Accelerating immuno-oncology innovation using humanized mouse models

Accelerating immuno-oncology innovation using humanized mouse models

Santi Suryani Chen, PhD.
21 September 2022
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Scaling up an AAV production platform to support clinical and commercial needs: challenges and opportunities

Scaling up an AAV production platform to support clinical and commercial needs: challenges and opportunities

I Iwuchukwu, T Cunningham, A Becerra
20 September 2022
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Addressing current challenges in lentiviral vector purification and associated analytics

Addressing current challenges in lentiviral vector purification and associated analytics

Bryan Zee
20 September 2022
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Overcoming quality and regulatory challenges to reliably take your cell & gene therapy to commercialization

Overcoming quality and regulatory challenges to reliably take your cell & gene therapy to commercialization

Andreas Wirth, Christoph Meyer
15 September 2022
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Achieve significantly increased adenovirus yield with density gradient ultracentrifugation: a comparative study

Achieve significantly increased adenovirus yield with density gradient ultracentrifugation: a comparative study

Shawn Sternisha
13 September 2022
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Successful workflows for GMP-compliant cell manufacturing & analytics

Successful workflows for GMP-compliant cell manufacturing & analytics

A Steinbach, A Manser, H Adoni
8 September 2022
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Round table discussion: Successful suspension-based viral vector manufacturing scale-up, from process development to clinics

Round table discussion: Successful suspension-based viral vector manufacturing scale-up, from process development to clinics

D Kole, L Giannunzio, C Peigné et al.
7 September 2022
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Complete system for AAV production for clinical production: Part 1 Upstream

Complete system for AAV production for clinical production: Part 1 Upstream

Dr. Jenny England, Jonathan Zmuda
2 September 2022
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Smart and scalable transfection platforms for start-to-finish AAV and LV development

Smart and scalable transfection platforms for start-to-finish AAV and LV development

Leisha Kopp
1 September 2022
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Automated and scalable closed-system platform for cell isolation and activation

Automated and scalable closed-system platform for cell isolation and activation

Hany Meås
31 August 2022
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International differences in cellular starting material quality and regulatory requirements

International differences in cellular starting material quality and regulatory requirements

B Kuker, P Machalik, S Ahmed et al.
30 August 2022
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Optimizing vector production and purification to enhance scalable AAV manufacturing

Optimizing vector production and purification to enhance scalable AAV manufacturing

Chantelle Gaskin, Jon Zmuda, PhD
25 August 2022
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Overcoming challenges in transitioning stem cell expansion from the laboratory to commercial production

Overcoming challenges in transitioning stem cell expansion from the laboratory to commercial production

Dr. Ben Josey
23 August 2022
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Emphasizing flows and functions – How intuitive design can enhance the functionality of an ATMP manufacturing facility

Emphasizing flows and functions – How intuitive design can enhance the functionality of an ATMP manufacturing facility

Shany Albalak
16 August 2022
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Forward engineering cell therapy production capabilities to save patient lives

Forward engineering cell therapy production capabilities to save patient lives

John Lee, PhD
11 August 2022
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Case Study: Streamlining AAV titer determination using variable pathlength technology

Case Study: Streamlining AAV titer determination using variable pathlength technology

Yan Chen, Joe Ferraiolo
10 August 2022
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High throughput viral titering of AAV throughout the production continuum

High throughput viral titering of AAV throughout the production continuum

Kelly Geosits
4 August 2022
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Optimizing cell proliferation and function for immunotherapy with recombinant growth factors & cytokines

Optimizing cell proliferation and function for immunotherapy with recombinant growth factors & cytokines

Martin P. Keough, PhD
3 August 2022
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Build vs buy dilemma: economics of manufacturing cell-based therapies

Build vs buy dilemma: economics of manufacturing cell-based therapies

Rupa Pike
28 July 2022
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Optimizing and standardizing the cryopreservation of cellular samples: new data and insights from the UK’s Advanced Therapy Treatment Centres program

Optimizing and standardizing the cryopreservation of cellular samples: new data and insights from the UK’s Advanced Therapy Treatment Centres program

Julie Meneghel, Sandeep Kumar
21 July 2022
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Mycoplasma testing regulatory guidance and strategies for cGMP cell and gene therapy manufacturing

Mycoplasma testing regulatory guidance and strategies for cGMP cell and gene therapy manufacturing

Michael Brewer
19 July 2022
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Scalability considerations when using cord blood as an allogeneic starting material

Scalability considerations when using cord blood as an allogeneic starting material

J Aho, W Van't Hof, A Kaestner
14 July 2022
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Adapting the power of density gradient separations for characterizing viral vector fullness

Adapting the power of density gradient separations for characterizing viral vector fullness

Shawn Sternisha
12 July 2022
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Autologous cell therapies - the path to commercial viability

Autologous cell therapies - the path to commercial viability

Joe Garrity
7 July 2022
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Transient expression of mRNA lipid nanoparticle-based chimeric antigen receptors for safe immunotherapy

Transient expression of mRNA lipid nanoparticle-based chimeric antigen receptors for safe immunotherapy

Sandy Tretbar
6 July 2022
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Feasibility of a Fixed Bed Bioreactor for Expansion of hESCs

Feasibility of a Fixed Bed Bioreactor for Expansion of hESCs

Hannah Rasby
30 June 2022
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Thinking translational: Things to consider in CAR T cell research workflows

Thinking translational: Things to consider in CAR T cell research workflows

Saskia Rösch, PhD
22 June 2022
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Transfection innovation for large scale AAV and LV – Considerations for process development through commercial manufacturing

Transfection innovation for large scale AAV and LV – Considerations for process development through commercial manufacturing

Geddy Hamblen
21 June 2022
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Accelerating cell therapy discovery & development with non-viral gene engineering

Accelerating cell therapy discovery & development with non-viral gene engineering

D Hermanson, X Patrinostro, S Silaika
16 June 2022
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Overcoming current challenges in immunotherapy drug development with patient-derived organoids

Overcoming current challenges in immunotherapy drug development with patient-derived organoids

Sylvia F. Boj
15 June 2022
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Optimizing mRNA purification conditions by using a High Throughput Screening approach

Optimizing mRNA purification conditions by using a High Throughput Screening approach

14 June 2022
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Taking a right first-time approach to optimize end-to-end viral vector manufacturing

Taking a right first-time approach to optimize end-to-end viral vector manufacturing

Hanna Lesch, Julien Depollier
9 June 2022
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Life on a chip - vascularized micro-tumor chips for mimicking clinical drug responses

Life on a chip - vascularized micro-tumor chips for mimicking clinical drug responses

Chris Hughes
8 June 2022
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Applying an HPLC analytical platform for mRNA process monitoring

Applying an HPLC analytical platform for mRNA process monitoring

Nejc Pavlin
7 June 2022
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Optimizing E. Coli cell growth performance with in-line, real-time OD600 (abs/mm) monitoring during the fermentation process

Optimizing E. Coli cell growth performance with in-line, real-time OD600 (abs/mm) monitoring during the fermentation process

Tanja Buch, Ramsey Shanbaky
1 June 2022
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Monitoring of circulating CAR T cells

Monitoring of circulating CAR T cells

A Graband, D Hünecke, D Bremm
31 May 2022
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Improving T cell therapy manufacturing processes with automation and scalability

Improving T cell therapy manufacturing processes with automation and scalability

Evan Zynda, PhD
26 May 2022
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Streamlined workflow solutions for cell and gene therapy analytics

Streamlined workflow solutions for cell and gene therapy analytics

Annika Graband
24 May 2022
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Strategic partnering to enable cell therapy commercialization

Strategic partnering to enable cell therapy commercialization

Jenessa Smith, Xavier de Mollerat du Jeu
12 May 2022
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Manufacturing considerations for viral and non-viral platform selection

Manufacturing considerations for viral and non-viral platform selection

V Slepushkin, A Noyes, A Hagerman
10 May 2022
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Process development excellence to de-risk and accelerate commercialization of cell and gene therapies

Process development excellence to de-risk and accelerate commercialization of cell and gene therapies

Behnam Baghbaderani
5 May 2022
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From cells to purified capsids: How to develop a scalable rAAV process

From cells to purified capsids: How to develop a scalable rAAV process

Åsa Hagner McWhirter
3 May 2022
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Strategic supply chain design: flexibility and scalability considerations for optimal facility design

Strategic supply chain design: flexibility and scalability considerations for optimal facility design

Niranjan Kulkarni, PhD, Grace Linton, RA, AIA, LEED AP BD+C
28 April 2022
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Removing technological barriers to efficient large-scale LV vector production

Removing technological barriers to efficient large-scale LV vector production

E Jackson-Holmes, M Neri, S G. Milian et al.
26 April 2022
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Process development innovations to improve gene therapy manufacturing

Process development innovations to improve gene therapy manufacturing

Jessica Hilmoe, Michael Shen
21 April 2022
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Automating cell manufacturing: customized solutions for research, development and industry

Automating cell manufacturing: customized solutions for research, development and industry

Marko Gogala
20 April 2022
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Applications and benefits of the CTS Rotea Counterflow Centrifugation System in cell therapy workflows

Applications and benefits of the CTS Rotea Counterflow Centrifugation System in cell therapy workflows

Carl Dargitz
13 April 2022
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Increasing productivity of IVT reaction using at-line monitoring by HPLC chromatography

Increasing productivity of IVT reaction using at-line monitoring by HPLC chromatography

Rok Sekirnik
12 April 2022
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Supply chain efficiency and sourcing for scaling your gene therapy operation

Supply chain efficiency and sourcing for scaling your gene therapy operation

Celine Martin, Don Young
7 April 2022
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Discovery to manufacturing: A continuum

Discovery to manufacturing: A continuum

Tony Hitchcock, Brian Fry
5 April 2022
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Scaling non-viral cell therapy approaches for solid tumour treatments

Scaling non-viral cell therapy approaches for solid tumour treatments

Evan Zynda, PhD, Kyle Jacoby, PhD
31 March 2022
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A scalable lentiviral vector production system based on stable producer cell lines

A scalable lentiviral vector production system based on stable producer cell lines

Roy Bin Liu
29 March 2022
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Scaling non-viral cell therapy approaches for solid tumor treatments

Scaling non-viral cell therapy approaches for solid tumor treatments

Evan Zynda, PhD, Kyle Jacoby, PhD
24 March 2022
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What does Plug-and-Play offer large-scale AAV manufacturing?

What does Plug-and-Play offer large-scale AAV manufacturing?

Margherita Neri
22 March 2022
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Flexible and scalable solutions for AAV viral vector production using a templated platform

Flexible and scalable solutions for AAV viral vector production using a templated platform

Eva Fong
17 March 2022
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Automated GMP-compliant PSC banking in a closed system

Automated GMP-compliant PSC banking in a closed system

Rafal Krol, PhD
15 March 2022
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Rapid translation of a cellular therapeutic: Choosing product & process development solutions for clinical manufacturing readiness

Rapid translation of a cellular therapeutic: Choosing product & process development solutions for clinical manufacturing readiness

Ashish Patel
10 March 2022
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Accelerate your cell and gene therapy workflows with next-generation analytical tools

Accelerate your cell and gene therapy workflows with next-generation analytical tools

8 March 2022
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Simplifying analytical development for viral vector production: robust and sensitive methods for common expression systems

Simplifying analytical development for viral vector production: robust and sensitive methods for common expression systems

3 March 2022
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Rethink CAR T cell therapy with a scalable RNA lipid nanoparticle platform

Rethink CAR T cell therapy with a scalable RNA lipid nanoparticle platform

Angela Zhang, PhD, Reka Geczy, PhD
1 March 2022
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Introducing Lonza’s AAV suspension transient transfection platform to de-risk your path to clinic

Introducing Lonza’s AAV suspension transient transfection platform to de-risk your path to clinic

24 February 2022
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Manufacturing of RCA-free adenoviral vectors

Manufacturing of RCA-free adenoviral vectors

Nico Scheer
22 February 2022
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AAV manufacturing process development using fast USP and DSP HPLC analytics

AAV manufacturing process development using fast USP and DSP HPLC analytics

Aleš Štrancar
17 February 2022
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How to monitor protein impurities to ensure consistent cell and gene therapy products

How to monitor protein impurities to ensure consistent cell and gene therapy products

Ejvind Mortz
15 February 2022
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TESSA technology: A new era for AAV manufacture

TESSA technology: A new era for AAV manufacture

Ryan Cawood
10 February 2022
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Exploring the charge heterogeneity in recombinant adeno-associated virus with imaged isoelectric focusing

Exploring the charge heterogeneity in recombinant adeno-associated virus with imaged isoelectric focusing

Julie Wei
8 February 2022
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The digital revolution: Technological innovations to enable automation in cell therapy manufacturing

The digital revolution: Technological innovations to enable automation in cell therapy manufacturing

S Chang, B Greenwald, K Roy
3 February 2022
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Accelerate process development with at-line concentration measurement

Accelerate process development with at-line concentration measurement

Joe Ferraiolo
1 February 2022
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Professionalizing mesenchymal stem cells for therapeutic benefit

Professionalizing mesenchymal stem cells for therapeutic benefit

Anthony Ting
20 January 2022
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Accelerating gene therapy development: from concept to clinic

Accelerating gene therapy development: from concept to clinic

S Gill, Q Liu, R Cawood
20 January 2022
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Abeona Therapeutics Evaluates a Scalable Suspension-based Platform for Production of Viral Vector for MPS-IIIA

Abeona Therapeutics Evaluates a Scalable Suspension-based Platform for Production of Viral Vector for MPS-IIIA

Phil Maples, Anne MacIntyre
18 January 2022
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Cell and gene therapy matures: Streamlining and smoothing the path to commercialization

Cell and gene therapy matures: Streamlining and smoothing the path to commercialization

Matt Hewitt, PhD
11 January 2022
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Automating the final cell therapy bioprocess step for robust CMC/GMP compliance

Automating the final cell therapy bioprocess step for robust CMC/GMP compliance

Tracy Moore, Delara Motlagh
11 January 2022
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Current technological trends and advancements in vector purification

Current technological trends and advancements in vector purification

C Gaskin, A Saksule, N PhD et al.
15 December 2021
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Putting the patient first: New modalities of manufacturing for cell therapy through real-time process changes

Putting the patient first: New modalities of manufacturing for cell therapy through real-time process changes

C White III, P Wang, D Wang
9 December 2021
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Developing stem cell therapies: expansion strategies and lessons learned

Developing stem cell therapies: expansion strategies and lessons learned

S PhD, MSc, L MD, MHSc, FRCPC, C PhD
8 December 2021
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Accelerating Plasmid Production by Optimizing Your Process Analytics

Accelerating Plasmid Production by Optimizing Your Process Analytics

Paul Mania
2 December 2021
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Enabling clinical grade manufacturing of gene-engineered NK cells

Enabling clinical grade manufacturing of gene-engineered NK cells

N Möker, P Evelyn Ullrich, R MD et al.
30 November 2021
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Magnetic selection for consistent cellular starting material in autologous cell therapy manufacture

Magnetic selection for consistent cellular starting material in autologous cell therapy manufacture

Kenneth Olsen, PhD, Rachel Perret, PhD
23 November 2021
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Achieving high non-viral transfection performance for cell therapy processing

Achieving high non-viral transfection performance for cell therapy processing

N Andronikou, T Phd, MD, J Fraietta
16 November 2021
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Advancing engineered cell and gene therapy with precision gene editing

Advancing engineered cell and gene therapy with precision gene editing

Danilo Maddalo
11 November 2021
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Automated cell expansion: Current technologies and trends

Automated cell expansion: Current technologies and trends

9 November 2021
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Considerations for developing scalable and efficient collection network processes

Considerations for developing scalable and efficient collection network processes

L Anderson, S Butler, A Montalvo,
28 October 2021
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Platform optimization for efficient AAV purification – insights from a CDMO

Platform optimization for efficient AAV purification – insights from a CDMO

Nicolas Laroudie, Vincent Ravault
26 October 2021
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Optimization of AAV production for high-yielding and scalable GMP processes

Optimization of AAV production for high-yielding and scalable GMP processes

M Porte, B Kondragunta, G PhD
20 October 2021
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cGMP manufacturing made easy – a case study by ElevateBio

cGMP manufacturing made easy – a case study by ElevateBio

Michael Paglia, Shannon Eaker
14 October 2021
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Gain deeper insights into the mechanisms of immune cell killing of tumor cells: accelerate your time to answer with integrated software analysis

Gain deeper insights into the mechanisms of immune cell killing of tumor cells: accelerate your time to answer with integrated software analysis

D Souders, T PhD, N Bevan et al.
6 October 2021
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The therapeutic gene editing solution – cell therapy for solid tumors

The therapeutic gene editing solution – cell therapy for solid tumors

B PhD, P PhD, J PhD et al.
30 September 2021
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GMP manufacturing for exosome-based therapies: the critical role of analytics and process design for clinical production and scale-up

GMP manufacturing for exosome-based therapies: the critical role of analytics and process design for clinical production and scale-up

Marcos Langtry, Davide Zocco
28 September 2021
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Get your non-viral T cell engineering process ready for clinical manufacturing

Get your non-viral T cell engineering process ready for clinical manufacturing

M Rietenbach, S Wild, K Patel
21 September 2021
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AAV manufacturing with stable producer cells for industrial scale vector production

AAV manufacturing with stable producer cells for industrial scale vector production

Ben Hudjetz, PhD
16 September 2021
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Scalable, flexible manufacture: simplifying cell & gene therapy production

Scalable, flexible manufacture: simplifying cell & gene therapy production

8 September 2021
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The setup and payoff: entering the clinic and the market efficiently by leveraging a platform lentiviral vector process

The setup and payoff: entering the clinic and the market efficiently by leveraging a platform lentiviral vector process

Kevin D Beck, PhD
1 September 2021
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Are you finishing strong in cell therapy manufacturing? Tackling your final fill and finish challenges with automation.

Are you finishing strong in cell therapy manufacturing? Tackling your final fill and finish challenges with automation.

Dalip Sethi, Annie Cunningham
31 August 2021
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Midstream unit operations: Unsung heroes in AAV process development

Midstream unit operations: Unsung heroes in AAV process development

Matthew Roach, Ratish Krishnan
18 August 2021
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Cell-based therapies for cancer treatment: leveraging advanced flow cytometry for greater clinical insight

Cell-based therapies for cancer treatment: leveraging advanced flow cytometry for greater clinical insight

N Ph.D., P Fan, T Laskowski, Ph.D.
5 August 2021
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Optimizing downstream purification of high-quality plasmid DNA for gene therapy and vaccine production

Optimizing downstream purification of high-quality plasmid DNA for gene therapy and vaccine production

Dr. Alejandro Becerra, Associate Prof. Dr. Johannes F. Buyel
3 August 2021
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Accelerating CAR-T process development: The power of process insight

Accelerating CAR-T process development: The power of process insight

Julia Hupfeld, Ph.D.
29 July 2021
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Expression systems for viral vector production: advantages of the Sf9 Baculovirus system and simple solutions to address its specific analytical challenges

Expression systems for viral vector production: advantages of the Sf9 Baculovirus system and simple solutions to address its specific analytical challenges

Yi Fang Lee, Srinath Kashi Ranganath
22 July 2021
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Assuring manufacturing and data integrity for cell and gene therapy regulatory compliance

Assuring manufacturing and data integrity for cell and gene therapy regulatory compliance

Jelena Jurlin, Dr. Dmitry Fridman
14 July 2021
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Delivering an end-to-end industrialization roadmap for autologous cell therapy

Delivering an end-to-end industrialization roadmap for autologous cell therapy

M PhD, J Garrity, W Bagni
6 July 2021
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Applying a closed, modular, semi-automated system to CAR T cell therapy manufacturing

Applying a closed, modular, semi-automated system to CAR T cell therapy manufacturing

Y Ji, S PhD, N PhD
29 June 2021
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Addressing the challenges of purification & quality control in gene therapy

Addressing the challenges of purification & quality control in gene therapy

D Bhattacharya, L Kopp, K PhD et al.
24 June 2021
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Strategies to advance the donor selection process for cell therapies to improve outcomes

Strategies to advance the donor selection process for cell therapies to improve outcomes

M Maiers, P Wang Petersdorf, K Wadsworth et al.
17 June 2021
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Overcoming purification challenges in antibody therapeutics manufacturing with subdomain-specific affinity solutions

Overcoming purification challenges in antibody therapeutics manufacturing with subdomain-specific affinity solutions

Laurens Sierkstra
10 June 2021
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Key considerations for maximizing LV and AAV production in transient transfection workflows

Key considerations for maximizing LV and AAV production in transient transfection workflows

L Kopp, D Larimore, A Dasgupta et al.
9 June 2021
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Navigating regulations - novel cell therapy platforms and their path to clinical manufacturing

Navigating regulations - novel cell therapy platforms and their path to clinical manufacturing

N Bauer, N Calhoun, A Davies et al.
27 May 2021
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Protein biomarkers in plasma: revealing biological insights into the tumor microenvironment

Protein biomarkers in plasma: revealing biological insights into the tumor microenvironment

Dr Genevieve Boland, Dr Arnav Mehta
20 May 2021
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Improving upon legacy vector and plasmid bioprocess technology for tomorrow’s advanced therapies

Improving upon legacy vector and plasmid bioprocess technology for tomorrow’s advanced therapies

M Lundgren, P Guterstam, H Ihre
18 May 2021
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Applying Warp Speed lessons to your ATMP manufacturing facility

Applying Warp Speed lessons to your ATMP manufacturing facility

J Bornholdt, C Heffernan, T Page et al.
12 May 2021
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From first collection to commercial launch: Streamlining your supply chain to support next generation therapies

From first collection to commercial launch: Streamlining your supply chain to support next generation therapies

Chris McClain, Aileen Baquiran
6 May 2021
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Key considerations for hMSC product and process development through clinical cGMP manufacturing

Key considerations for hMSC product and process development through clinical cGMP manufacturing

J Rowley, R Barcia, J Candiello et al.
28 April 2021
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Key lessons for cell & gene therapy and mRNA therapeutic development from COVID-19 mRNA vaccine approvals

Key lessons for cell & gene therapy and mRNA therapeutic development from COVID-19 mRNA vaccine approvals

S Zobbi, V PhD, C Kröner
22 April 2021
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Ultrahigh-content imaging helps to identify CAR target candidates against pancreatic adenocarcinoma

Ultrahigh-content imaging helps to identify CAR target candidates against pancreatic adenocarcinoma

Dr. Daniel Schäfer
20 April 2021
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Scalable suspension LVV production platforms for cell and gene therapy

Scalable suspension LVV production platforms for cell and gene therapy

S Sanyal, M Haller, Y Shin
13 April 2021
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Navigating current translational challenges in establishing clinical CAR T cell therapy manufacture

Navigating current translational challenges in establishing clinical CAR T cell therapy manufacture

D García Guerreiro, D Kassim, D Dudley et al.
7 April 2021
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How crucial is automation of fill and finish? Considerations to overcome challenges of the final formulation, fill and finish process.

How crucial is automation of fill and finish? Considerations to overcome challenges of the final formulation, fill and finish process.

Dalip Sethi
30 March 2021
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Studying solid tumors and their micro-environment based on automated large-scale 3D fluorescence imaging

Studying solid tumors and their micro-environment based on automated large-scale 3D fluorescence imaging

Nizar Yousif, Hussein Hamzeh
25 March 2021
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FectoVIR®-AAV, the new tool to enhance recombinant AAV production for gene therapy

FectoVIR®-AAV, the new tool to enhance recombinant AAV production for gene therapy

Elisa Da Silva Ferrada, Valerie Lang
24 March 2021
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Harnessing the power of tumor-infiltrating lymphocytes for cell therapy

Harnessing the power of tumor-infiltrating lymphocytes for cell therapy

D Pelletier, F PhD, N Monhasery
3 March 2021
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Large-scale LVV production: from industry-leading process development to high quality GMP vector

Large-scale LVV production: from industry-leading process development to high quality GMP vector

D Vallanti, P Aiuti, D Sabatino
25 February 2021
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Exploring the capabilities of a versatile, novel, automated closed system for cell and gene therapy manufacturing

Exploring the capabilities of a versatile, novel, automated closed system for cell and gene therapy manufacturing

Premkumar Jayaraman, PhD, Sarah Daoudi
16 February 2021
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Fitting product to process: raw materials customization for cell therapy manufacturing success

Fitting product to process: raw materials customization for cell therapy manufacturing success

J Tomtishen III, L PhD, L PhD et al.
11 February 2021
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Supporting development of mRNA-based therapies by addressing large scale purification challenges

Supporting development of mRNA-based therapies by addressing large scale purification challenges

Kelly Flook
9 February 2021
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Breaking barriers in viral vector titer analysis speed, volume, and data quality

Breaking barriers in viral vector titer analysis speed, volume, and data quality

R PhD, J PhD, K PhD et al.
27 January 2021
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Focusing on donor characteristics and efficient selection to improve allogeneic cell therapy outcomes

Focusing on donor characteristics and efficient selection to improve allogeneic cell therapy outcomes

M MS, B PhD, D Gibson et al.
21 January 2021
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Case study: Optimization of lentiviral vector production from early stages to GMP

Case study: Optimization of lentiviral vector production from early stages to GMP

C Wartel-Weill, N Elizalde, R de Maturana
19 January 2021
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Raw materials of biological origin: navigating regulatory requirements for cell therapies

Raw materials of biological origin: navigating regulatory requirements for cell therapies

Marlin Frechette, Dominic Clarke
13 January 2021
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Streamlining CAR-T manufacture: reducing complexity and improving robustness through acoustic cell processing

Streamlining CAR-T manufacture: reducing complexity and improving robustness through acoustic cell processing

Jordan Croteau
9 December 2020
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The right time to move to an automated manufacturing system like the Cocoon platform: the when, the why, and the how

The right time to move to an automated manufacturing system like the Cocoon platform: the when, the why, and the how

Donna Rill
3 December 2020
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Innovative capillary electrophoresis techniques for gene therapy R&D

Innovative capillary electrophoresis techniques for gene therapy R&D

Chris Heger, PhD, Julie Wei
1 December 2020
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Focus on allogeneic CAR-Ts manufacturing challenges and solutions

Focus on allogeneic CAR-Ts manufacturing challenges and solutions

Alex Sargent, Behnam Baghbaderani
5 November 2020
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Scalable AAV manufacturing – Addressing challenges across the workflow

Scalable AAV manufacturing – Addressing challenges across the workflow

K Thompson, C Liu, J Li et al.
29 October 2020
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Evolving the role of gene editing in cell therapy

Evolving the role of gene editing in cell therapy

J Frampton, T Thwaites, T Meissner
6 October 2020
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The multi-modal manufacturing movement - you don't need to know the future to be ready for it

The multi-modal manufacturing movement - you don't need to know the future to be ready for it

Peter Walters, Noel Maestre
30 September 2020
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Scalable commercial manufacturing: a key strategic element for success of next generation exosome-based cell-free therapies

Scalable commercial manufacturing: a key strategic element for success of next generation exosome-based cell-free therapies

Behzad Mahdavi, Senthil Ramaswamy
24 September 2020
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Optimizing antibody discovery strategy for clinical success of next-gen immuno-oncology therapeutics

Optimizing antibody discovery strategy for clinical success of next-gen immuno-oncology therapeutics

Patrick Ott, Ilse Roodink
23 September 2020
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Get your assay in gear – removing analytical bottlenecks on the path to clinical readiness

Get your assay in gear – removing analytical bottlenecks on the path to clinical readiness

Ian Gaudet
8 September 2020
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Identifying the critical factors for commercial-scale viral vector process development and manufacturing

Identifying the critical factors for commercial-scale viral vector process development and manufacturing

Behnam Baghbaderani, Xin Swanson
26 August 2020
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Realizing flexible automation – Closing gaps to meet industry needs

Realizing flexible automation – Closing gaps to meet industry needs

K Niss, S Thompson, M Lowdell
12 August 2020
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Size matters: ensuring donor pool sustainability and cell therapy supply chain success when scaling up and out

Size matters: ensuring donor pool sustainability and cell therapy supply chain success when scaling up and out

C Learn, A Agarwal, R Hornung
6 August 2020
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Scalable and efficient AAV production process with new Fibro chromatography technology

Scalable and efficient AAV production process with new Fibro chromatography technology

Laura Adamson-Small
30 July 2020
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Manufacturing of endogenous, non-engineered, antigen specific T cells against tumor targets

Manufacturing of endogenous, non-engineered, antigen specific T cells against tumor targets

Ali Mohamed, Megan Ciarlo
14 July 2020
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Challenges of cell collections for cell therapy manufacturing: what do we want in the bag?

Challenges of cell collections for cell therapy manufacturing: what do we want in the bag?

E Valdez, J Beltzer, S Soni et al.
24 June 2020
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Simplifying GMP CAR-T and CAR NK cell therapy manufacturing processes

Simplifying GMP CAR-T and CAR NK cell therapy manufacturing processes

M Luevano, X Wang, S Fricke et al.
9 June 2020
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Enabling the industrialization of human induced pluripotent stem cell-based therapies

Enabling the industrialization of human induced pluripotent stem cell-based therapies

Krishna Panchalingam, Inbar Friedrich Ben-Nun
4 June 2020
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AAV downstream processing for industrial scale production – moving towards commercial manufacturing

AAV downstream processing for industrial scale production – moving towards commercial manufacturing

Orjana Terova, Mikhail Goldfarb
20 May 2020
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From vein to vein: how starting material quality impacts the manufacturing and success of next-generation therapies

From vein to vein: how starting material quality impacts the manufacturing and success of next-generation therapies

C McClain, M Giedlin, B Baghbaderani et al.
7 May 2020
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Stable AAV producer cell lines: elevating vector manufacturing

Stable AAV producer cell lines: elevating vector manufacturing

Silke Wissing
5 May 2020
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Advances in gene therapy delivery: next-generation transfection reagent for large-scale AAV manufacturing

Advances in gene therapy delivery: next-generation transfection reagent for large-scale AAV manufacturing

Malik Hellal
29 April 2020
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Scaling up viral vector manufacturing with adherent and suspension cell cultures

Scaling up viral vector manufacturing with adherent and suspension cell cultures

C Glover, R Legmann, S Gupta
21 April 2020
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Lentiviral vector process to accelerate cell and gene therapy clinical development and commercialization

Lentiviral vector process to accelerate cell and gene therapy clinical development and commercialization

Kevin Beck
16 April 2020
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Enabling new cell therapies with GMP-compliant multiparametric cell sorting

Enabling new cell therapies with GMP-compliant multiparametric cell sorting

S Elliman, I Lai, J Dunne
18 March 2020
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Ensuring source material consistency and continuity for commercialization of advanced therapies

Ensuring source material consistency and continuity for commercialization of advanced therapies

Amy Shaw, Christopher Good
12 March 2020
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Development and validation of quantitative real-time PCR for the detection of residual HEK-293 host cell DNA

Development and validation of quantitative real-time PCR for the detection of residual HEK-293 host cell DNA

Kara Norman
27 February 2020
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Multi-modal facilities: delivering flexible, future-proof ATMP manufacturing

Multi-modal facilities: delivering flexible, future-proof ATMP manufacturing

Emily Thompson, Noel Maestre
12 February 2020
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Scaling up and out: developing a commercial supply chain strategy to successfully deliver next-generation therapies

Scaling up and out: developing a commercial supply chain strategy to successfully deliver next-generation therapies

T Tripp, J Aho, P Niedzwiedz
6 February 2020
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Capsid titre quantification for AAV-based therapeutics

Capsid titre quantification for AAV-based therapeutics

John Chappell, Tomasz Witkos
30 January 2020
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Collaborative development of a new fill/finish instrument

Collaborative development of a new fill/finish instrument

A Schlinker, C Wegener, D Smith et al.
28 January 2020
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A pragmatic approach to the buy vs build manufacturing dilemma

A pragmatic approach to the buy vs build manufacturing dilemma

N Haderbache, C Houts, J Phillips
16 January 2020
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Combining state-of-the-art production, purification and analytics to optimize AAV manufacturing for clinical and commercial gene therapies

Combining state-of-the-art production, purification and analytics to optimize AAV manufacturing for clinical and commercial gene therapies

B Pence, R Snyder, K Torchilin
10 December 2019
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In-depth case study webinar: how MolMed achieved large-scale GMP production of LV and RV Vectors

In-depth case study webinar: how MolMed achieved large-scale GMP production of LV and RV Vectors

Clive Glover
4 December 2019
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Key steps to industrialize your process and de-risk your pathway to commercialization in cell and gene therapy

Key steps to industrialize your process and de-risk your pathway to commercialization in cell and gene therapy

Behnam Baghbaderani
21 November 2019
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Meeting the scalability challenge of downstream viral vector purification

Meeting the scalability challenge of downstream viral vector purification

S Brittle, S Merino, X Fu et al.
12 November 2019
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Let’s talk integration

Let’s talk integration

Nina Bauer
29 October 2019
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Rapid mycoplasma PCR QC testing for cell and gene therapies

Rapid mycoplasma PCR QC testing for cell and gene therapies

Renate Rosengarten, Angeliki Grammenos
24 October 2019
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Moving towards decentralized manufacturing of cell and gene therapy products through automation

Moving towards decentralized manufacturing of cell and gene therapy products through automation

I Johnston, N Medcalf, Á Urbano-Ispizua et al.
17 October 2019
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A bespoke solution to cell therapy manufacturing: the Cocoon platform

A bespoke solution to cell therapy manufacturing: the Cocoon platform

26 September 2019
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A lens on the final formulation and fill & finish process: considerations for process automation and device development

A lens on the final formulation and fill & finish process: considerations for process automation and device development

K Massey, M Covington, D Sethi
18 September 2019
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No room for error: preparing for inevitable variability in the cell and gene therapy supply chain

No room for error: preparing for inevitable variability in the cell and gene therapy supply chain

J Margolis, L Fox, R Hornung et al.
5 September 2019
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Accelerating advancement in gene therapy by improving downstream purification of viral vectors

Accelerating advancement in gene therapy by improving downstream purification of viral vectors

Orjana Terova, Hetal Brahmbhatt
27 August 2019
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Optimizing the workflow for therapeutic viral vectors – upstream and downstream

Optimizing the workflow for therapeutic viral vectors – upstream and downstream

S Hoover, L Chan, F Bellintani
18 July 2019
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Closing the production gap in gene therapy – A scalable helper virus-free AAV production platform

Closing the production gap in gene therapy – A scalable helper virus-free AAV production platform

N Faust, C Glover, A Topping et al.
11 July 2019
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NextGen now - Delivering tomorrow’s facilities today

NextGen now - Delivering tomorrow’s facilities today

Marc Pelletier, Ryan McDonough
25 June 2019
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Implementation of biopreservation best practices to address a critical component of cell and gene therapy manufacturing

Implementation of biopreservation best practices to address a critical component of cell and gene therapy manufacturing

Alireza Abazari
18 June 2019
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Enabling the next level of pluripotent stem-cell based therapies, from bench to commercialization

Enabling the next level of pluripotent stem-cell based therapies, from bench to commercialization

Puspa Pandey, Fan Yang
13 June 2019
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The power of ultra-high content and 3D imaging for the identification and characterisation of new CAR-T cell targets

The power of ultra-high content and 3D imaging for the identification and characterisation of new CAR-T cell targets

Olaf Hardt, Uwe Schroeer
22 May 2019
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Gaining critical characterization insights for development of CAR-T therapies for solid tumors

Gaining critical characterization insights for development of CAR-T therapies for solid tumors

John O’Rourke, Janani Krishnamurthy
16 May 2019
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Using patient outcomes data to inform and advance the development of emerging cell and gene therapies

Using patient outcomes data to inform and advance the development of emerging cell and gene therapies

D Henke, C Wilfong, M Pasquini
9 May 2019
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Optimizing process development to simplify manufacturing scale up of therapeutic viral vectors

Optimizing process development to simplify manufacturing scale up of therapeutic viral vectors

C Lorenz, V Kedinger, R Legmann et al.
17 April 2019
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Planning for success: emerging GMP-grade raw materials & technologies for cell therapy

Planning for success: emerging GMP-grade raw materials & technologies for cell therapy

S Kevlahan, L Fox, A Herrero et al.
27 March 2019
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Critical components for developing and managing expansive, high-performing collection networks

Critical components for developing and managing expansive, high-performing collection networks

A Hines, R Smith, J Vitale et al.
14 March 2019
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Designing GMP-friendly cell and gene therapy manufacturing processes

Designing GMP-friendly cell and gene therapy manufacturing processes

M Papadimitrious, X Wang, B Murphy
6 March 2019
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Managing starting material stability to maximize manufacturing flexibility and downstream efficiency

Managing starting material stability to maximize manufacturing flexibility and downstream efficiency

David Smith
21 February 2019
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Made-for-purpose manufacturing solutions - The key to commercialization

Made-for-purpose manufacturing solutions - The key to commercialization

Brian Dutra, Shirae Leslie
31 January 2019
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Addressing the challenges of preserving cell and gene therapies

Addressing the challenges of preserving cell and gene therapies

Q Rafiq, A Schlinker, D Maier
18 January 2019
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Evaluation of Poros AAVX Pan-Affinity Resin for rAAV purification and cGMP Manufacturing

Evaluation of Poros AAVX Pan-Affinity Resin for rAAV purification and cGMP Manufacturing

Daniel Hurwit
18 December 2018
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Real-world insights into automated solutions for cell & gene therapy bioprocessing

Real-world insights into automated solutions for cell & gene therapy bioprocessing

B Levine, G Bauer, J Beltzer
12 November 2018
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Scalable, helper virus-free AAV production with stable CAP-GT producer cell lines

Scalable, helper virus-free AAV production with stable CAP-GT producer cell lines

Nicole Faust
8 November 2018
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Latest advances in automated platforms for autologous cell & gene therapy manufacturing

Latest advances in automated platforms for autologous cell & gene therapy manufacturing

E Abraham, D Kuijstermans, Y Shi
25 October 2018
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Strategies to relieve the burden on apheresis & collection centers

Strategies to relieve the burden on apheresis & collection centers

A Hines, G Whitehead, H Steinmetz
11 October 2018
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Making it happen: the road to commercial scale cell therapy manufacturing

Making it happen: the road to commercial scale cell therapy manufacturing

Y Levinson, T Richardson, I Friedrich Ben-Nun
27 September 2018
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Development of a purification step for several AAV serotypes using POROS™ CaptureSelect™ AAVX affinity chromatography

Development of a purification step for several AAV serotypes using POROS™ CaptureSelect™ AAVX affinity chromatography

Magali Toueille
19 July 2018
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Standardized techniques for navigating the cell and gene therapy supply chain

Standardized techniques for navigating the cell and gene therapy supply chain

Jamie Margolis
10 July 2018
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Advances in CAR-T manufacture – Bridging the commercialization gaps

Advances in CAR-T manufacture – Bridging the commercialization gaps

I Johnston, K Roy, G Russotti
28 June 2018
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Development & manufacture of next-generation viral vectors for gene therapy

Development & manufacture of next-generation viral vectors for gene therapy

Anandita Seth
20 June 2018
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Challenges of cell therapy manufacturing: automation and disposables – the hand and the glove

Challenges of cell therapy manufacturing: automation and disposables – the hand and the glove

Natasha Boghosian, Brian Hanrahan
10 May 2018
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Overcoming challenges with the supply of plasmid DNA & other raw materials for gene therapy manufacture

Overcoming challenges with the supply of plasmid DNA & other raw materials for gene therapy manufacture

J Brown, M McIntyre, C Simpson et al.
17 April 2018
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Meeting scalability challenges for autologous cell-based manufacturing with automated closed-system solutions

Meeting scalability challenges for autologous cell-based manufacturing with automated closed-system solutions

Giulia Detela
8 March 2018
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GMP raw materials for cell therapy manufacture: what, when and how?

GMP raw materials for cell therapy manufacture: what, when and how?

J Stanton, J Tomtishen III, D Wotta
22 February 2018
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Commercial-scale viral vector manufacture: technical challenges & strategic implications

Commercial-scale viral vector manufacture: technical challenges & strategic implications

M Kelly, C Glover, R Snyder
14 February 2018
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Case studies in cell & gene therapy process optimization

Case studies in cell & gene therapy process optimization

David DiGiusto, Alaina Schlinker
18 January 2018
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Built to scale: strategic considerations to meet production demands in cell and gene therapy

Built to scale: strategic considerations to meet production demands in cell and gene therapy

S Ward, I Gaudet, H Embree
9 January 2018
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Cell & Gene Therapies for Rare Diseases: Navigating the Pathway to Market

Cell & Gene Therapies for Rare Diseases: Navigating the Pathway to Market

S Kili, G MacKay, S Washer
19 December 2017
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Automation of cell and gene therapy manufacturing: from vein to vein

Automation of cell and gene therapy manufacturing: from vein to vein

Q Rafiq, A Brown, A Chandra et al.
15 November 2017
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Cell & gene therapy manufacturing: key factors influencing manufacturing business models

Cell & gene therapy manufacturing: key factors influencing manufacturing business models

B Nelsen, K Warren, A Dulgar-Tulloch et al.
31 October 2017
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Optimizing supply chain design to ensure commercial success - The journey is as important as the destination

Optimizing supply chain design to ensure commercial success - The journey is as important as the destination

Simon Ellison, Kristen Franklin
12 September 2017
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Addressing the critical bottlenecks in the cell & gene therapy manufacturing pathway

Addressing the critical bottlenecks in the cell & gene therapy manufacturing pathway

P Zandstra, D Baksh, K Roy et al.
21 June 2017
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Advances in preserving, storing and managing the supply chain

Advances in preserving, storing and managing the supply chain

Simon Ellison, Francis Meacle
24 May 2017
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The latest developments in CAR-T cell manufacturing

The latest developments in CAR-T cell manufacturing

Isabelle Riviere
27 April 2017
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“One Word: Plastics” – The Role of Material Science in Cell Therapy Manufacturing

“One Word: Plastics” – The Role of Material Science in Cell Therapy Manufacturing

Natasha Boghosian, Katie Campbell
4 April 2017
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Advances in viral vector technology: Anc-AAV & evolutionary guided vector design

Advances in viral vector technology: Anc-AAV & evolutionary guided vector design

Luk Vandenberghe, Dirk Grimm
28 February 2017
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Automation of cell & gene therapy manufacture: challenges, options & opportunities for innovation

Automation of cell & gene therapy manufacture: challenges, options & opportunities for innovation

Q Rafiq, B Hanrahan, B Mistry et al.
7 December 2016
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