Vol 7 Issue 1

CELL AND GENE THERAPY INSIGHTS

Vol 7 Issue 1

Cell and Gene Therapy Insights Vol 7 Issue 1

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Featuring

Issue Spotlight: Preclinical/translational tools and strategies
Other articles
Webinars

Preclinical/translational tools and strategies

Bruce Bunnell

Guest Editor:

Bruce Bunnell, Professor and Chair at UNT Health Science Center

Foreword

Preclinical/translational tools & strategies

Preclinical/translational tools & strategies

Bruce A Bunnell

24 February 2021

Editorial

Accelerating preclinical development for AAV based gene therapies: bridging the gap between discovery and clinical development

Accelerating preclinical development for AAV based gene therapies: bridging the gap between discovery and clinical development

Louise Rodino-Klapac

24 February 2021

Expert Insight

Modelling late-onset diseases with induced pluripotent stem cells: a matter of time management

Modelling late-onset diseases with induced pluripotent stem cells: a matter of time management

Charlotte Cossins, Paul J Fairchild

15 February 2021

The T cell therapy field faces preclinical and translational R&D challenges as it targets more complex diseases

The T cell therapy field faces preclinical and translational R&D challenges as it targets more complex diseases

G Waanders, S Raffegerst, P Prinz-Schulz et al.

15 February 2021

Animal models of disease: preclinical to clinical gene therapy translatability

Animal models of disease: preclinical to clinical gene therapy translatability

Erika Matsumoto Plata, Carlos R Plata-Salamán

11 February 2021

Commentary

Expediting novel ex vivo HSC gene therapies to the clinic: a preclinical perspective

Expediting novel ex vivo HSC gene therapies to the clinic: a preclinical perspective

G Leoni, A Lambert, C Hudson et al.

24 February 2021

FastFacts

Identify and select optimal T cell phenotypes

Identify and select optimal T cell phenotypes

22 February 2021

Podcast

On a mission to bring single-cell sequencing to cell and gene therapy

On a mission to bring single-cell sequencing to cell and gene therapy

24 February 2021

Interview

On a mission to bring single-cell sequencing to cell and gene therapy

On a mission to bring single-cell sequencing to cell and gene therapy

24 February 2021

Beginning gene therapy preclinical development with the end in mind: from preclinical to economic modelling

Beginning gene therapy preclinical development with the end in mind: from preclinical to economic modelling

Olivier Negre, PhD

16 February 2021

Journal articles

Expert Insight

Business Insight: cell & gene therapy

Business Insight: cell & gene therapy

J Mulryne, D Beatriz San Martin, J Schmidt et al.

1 February 2021

Innovator Insight

Optimization of AAV process development: transfection matters

Optimization of AAV process development: transfection matters

K Wosnitzka, S Pariag, H Trottin et al.

14 January 2021

FastFacts

The importance of a strong collection cell collection network during the COVID-19 pandemic

The importance of a strong collection cell collection network during the COVID-19 pandemic

Chris McClain, MBA

11 February 2021

Podcast

Get in line: developing in-process analytical tools for gene therapy applications

Get in line: developing in-process analytical tools for gene therapy applications

René Gantier, Ramsey Shanbaky, Jay West

10 February 2021

Interview

A stepwise approach to process optimization in cellular immunotherapy development

A stepwise approach to process optimization in cellular immunotherapy development

24 February 2021

Get in line: developing in-process analytical tools for gene therapy applications

Get in line: developing in-process analytical tools for gene therapy applications

10 February 2021

Translation Insight

Flow cytometric analysis for cellular therapy products: design and practical considerations

Flow cytometric analysis for cellular therapy products: design and practical considerations

Alison J Thomson, Laura Bailey, John DM Campbell

26 January 2021

Case study: Optimization of lentiviral vector production from early stages to GMP

Case study: Optimization of lentiviral vector production from early stages to GMP

C Wartel-Weill PhD, N Elizalde PhD, R López de Maturana PhD

19 January 2021

Breaking barriers in viral vector titer analysis speed, volume, and data quality

Breaking barriers in viral vector titer analysis speed, volume, and data quality

R Durham PhD, J Stanta PhD, K Hanson PhD et al.

27 January 2021

Supporting development of mRNA-based therapies by addressing large scale purification challenges

Supporting development of mRNA-based therapies by addressing large scale purification challenges

Kelly Flook

9 February 2021

Exploring the capabilities of a versatile, novel, automated closed system for cell and gene therapy manufacturing

Exploring the capabilities of a versatile, novel, automated closed system for cell and gene therapy manufacturing

Premkumar Jayaraman PhD, Sarah Daoudi

16 February 2021

Large-scale LVV production: from industry-leading process development to high quality GMP vector

Large-scale LVV production: from industry-leading process development to high quality GMP vector

G Vallanti, A Aiuti, M Sabatino

25 February 2021

Harnessing the power of tumor-infiltrating lymphocytes for cell therapy

Harnessing the power of tumor-infiltrating lymphocytes for cell therapy

S Pelletier PhD, F Eppler PhD, N Monhasery PhD