Vol 7 Issue 6

CELL AND GENE THERAPY INSIGHTS

June 2021 Issue

Vol 7 Issue 6

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Featuring

Issue Spotlight: Gene delivery platform evolution
Vector characterization & analytics 2021
Other articles
Webinars

SPOTLIGHT

Gene delivery platform evolution

Editorial

Expanding gene therapy and gene editing strategies to large and complex indications

Expanding gene therapy and gene editing strategies to large and complex indications

Carmen Unzu, Florie Borel
30 June 2021
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Innovator Insight

Scalable upstream process development for the suspension-based production of lentiviral vectors for CAR T cell therapies with multiparallel & benchtop bioreactor systems & DoE methodology

Scalable upstream process development for the suspension-based production of lentiviral vectors for CAR T cell therapies with multiparallel & benchtop bioreactor systems & DoE methodology

Diana Riethmüller, Dr Alengo Nyamay’antu, Dr Franziska Bollmann
8 July 2021
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FastFacts

Cell and gene manufacturing: a case study approach to overcoming challenges – expert perspectives and solutions

Cell and gene manufacturing: a case study approach to overcoming challenges – expert perspectives and solutions

Steven Thompson
8 July 2021
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Plasmid processing for mRNA, gene therapy and other vector applications

Plasmid processing for mRNA, gene therapy and other vector applications

Henrik Ihre
30 June 2021
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Viewpoint

The dose makes the poison: next generation AAV vectors can save the day

The dose makes the poison: next generation AAV vectors can save the day

Julia Fakhiri, Jihad El Andari
13 July 2021
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A bright future for lipid nanoparticles in gene therapy

A bright future for lipid nanoparticles in gene therapy

Hongwei Zhang
8 July 2021
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Next-generation viral vector platforms for gene therapy, vaccine, and oncolytic virotherapy applications

Next-generation viral vector platforms for gene therapy, vaccine, and oncolytic virotherapy applications

Inanç Ortaç
21 June 2021
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Interview

Next steps in AAV preclinical and translational R&D

Next steps in AAV preclinical and translational R&D

Anna Tretiakova PhD, Shari Gordon
1 July 2021
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Coming of age: taking the next steps with non-viral gene delivery

Coming of age: taking the next steps with non-viral gene delivery

Matt Stanton
29 June 2021
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Progressing genetic medicines at the interface of gene therapy and gene editing

Progressing genetic medicines at the interface of gene therapy and gene editing

Dr Albert Seymour
14 June 2021
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Vectors FOCUS

Vector characterization & analytics 2021

Innovator Insight

Addressing the challenges of purification and quality control in gene therapy

Addressing the challenges of purification and quality control in gene therapy

A Bhattacharya, A Chang, L Kopp et al.
24 August 2021
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COVID-19 mRNA vaccine approvals: key lessons for cell & gene therapy and mRNA therapeutic development

COVID-19 mRNA vaccine approvals: key lessons for cell & gene therapy and mRNA therapeutic development

J Barberio, C Kröner, V Indurthi et al.
24 July 2021
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FastFacts

Slope spectroscopy for gene therapy applications

Slope spectroscopy for gene therapy applications

Paul Mania
10 August 2021
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Development & validation of a robust commercial solution for measuring residual kanamycin-resistant plasmid DNA

Development & validation of a robust commercial solution for measuring residual kanamycin-resistant plasmid DNA

Tania Chakrabarty
9 August 2021
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Viewpoint

Recent evolution in Process Analytical Technology for viral vectors

Recent evolution in Process Analytical Technology for viral vectors

Tony Bou Kheir
20 August 2021
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Interview

The A to Z of QbD

The A to Z of QbD

Michael Lehmicke
15 June 2021
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Journal articles

Innovator Insight

Lentiviral vectors: key challenges and new developments

Lentiviral vectors: key challenges and new developments

Natalia Elizalde, PhD, Juan Carlos Ramírez, PhD
23 June 2021
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FastFacts

Dedicated regulatory support packages for TheraPEAK® GMP Solutions

Dedicated regulatory support packages for TheraPEAK® GMP Solutions

Hippolitus Odukwu
21 June 2021
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Mycoplasma detection in cell therapy products: GMP-compliant implementation & validation of a commercial real-time PCR assay for routine quality control & lot release

Mycoplasma detection in cell therapy products: GMP-compliant implementation & validation of a commercial real-time PCR assay for routine quality control & lot release

Valentina Becherucci
20 June 2021
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Interview

Regulatory CMC in cell and gene therapy: navigating an evolving space

Regulatory CMC in cell and gene therapy: navigating an evolving space

Lawrence C. Starke
26 May 2021
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Webinars