Vol 8 Issue 10

CELL AND GENE THERAPY INSIGHTS

November 2022 Issue

Vol 8 Issue 10

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Featuring

Issue Spotlight: Cell therapy bioprocessing
Raw & starting materials quality, sourcing and management 2022
Other articles
Webinars

SPOTLIGHT

Cell therapy bioprocessing
Alexey Bersenev
Guest Editor:
Alexey Bersenev, Assistant Professor of Clinical Laboratory Medicine at Yale University

Expert Roundtable

AAV process development & scale-up

AAV process development & scale-up

Catherine Cancian, Karen Doucette, Reinout Hesselink
7 March 2023
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Commentary

Cell therapy 101 (part 1)Challenges of early clinical development: a ‘thumbnail sketch’

Cell therapy 101 (part 1)Challenges of early clinical development: a ‘thumbnail sketch’

Michael D Leek
29 November 2022
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FastFacts

A flexible & fully automated process for CAR T cell manufacturing

A flexible & fully automated process for CAR T cell manufacturing

Sophia Lollies
11 November 2022
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Standardizing flow cytometric assays during cell manufacturing

Standardizing flow cytometric assays during cell manufacturing

Annika Graband
3 November 2022
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Viewpoint

Key considerations for early investment in the process development of cell-based therapeutics

Key considerations for early investment in the process development of cell-based therapeutics

Kelly Kemp, Sebastian Rieck
23 November 2022
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Producing cell-based therapeutic products with lot-to-lot consistency from highly variable starting cell products

Producing cell-based therapeutic products with lot-to-lot consistency from highly variable starting cell products

William E Janssen, Scott R Burger
2 November 2022
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Interview

Enabling GMP-ready cell sorting for cell and gene therapy manufacturing

Enabling GMP-ready cell sorting for cell and gene therapy manufacturing

Aditi Singh
8 February 2023
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Advancing cell therapy manufacturing towards industry 4.0

Advancing cell therapy manufacturing towards industry 4.0

Thomas Bollenbach
21 November 2022
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Enabling scalable manufacture of exosomes for future clinical & commercial requirements

Enabling scalable manufacture of exosomes for future clinical & commercial requirements

Peter Jones
21 October 2022
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Supply Chain FOCUS

Raw & starting materials quality, sourcing and management 2022

Innovator Insight

Cell & gene therapy orchestration: supply chain management in real-time

Cell & gene therapy orchestration: supply chain management in real-time

Andreas Göbel, Dr Camila Mendes
9 November 2022
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Viewpoint

Building resilience into post-pandemic cell & gene therapy supply chains

Building resilience into post-pandemic cell & gene therapy supply chains

Tiffany Clement, Cheryl Cox
18 November 2022
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The living cell supply chain: a product-specific, rational approach to management of cellular starting material donors & donations

The living cell supply chain: a product-specific, rational approach to management of cellular starting material donors & donations

William E Janssen, Scott R. Burger
18 November 2022
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Interview

Innovating in iPSC differentiation & engineering

Innovating in iPSC differentiation & engineering

Emily Titus
30 November 2022
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The drive for standardization in cellular starting material collection for cell therapy

The drive for standardization in cellular starting material collection for cell therapy

Anh Nguyen Jones
22 November 2022
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Journal articles

Expert Insight

Expanding the analytical toolbox to address complex cell-based therapies

Expanding the analytical toolbox to address complex cell-based therapies

Nathan C Manley, Samuel JI Blackford
18 November 2022
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Innovator Insight

Roadmap to success in AAV purification. In-process control, high throughput & novel column modalities as necessary means for control over scalable AAV process

Roadmap to success in AAV purification. In-process control, high throughput & novel column modalities as necessary means for control over scalable AAV process

R Žigon, M Tajnik Sbaizero, I Petrović Koshmak et al.
18 November 2022
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Process development excellence to de-risk & accelerate commercialization of cell & gene therapies

Process development excellence to de-risk & accelerate commercialization of cell & gene therapies

Behnam Ahmadian Baghbaderani
17 November 2022
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IsoTag™AAV: an innovative, scalable & non-chromatographic method for streamlined AAV manufacturing

IsoTag™AAV: an innovative, scalable & non-chromatographic method for streamlined AAV manufacturing

J Haley, J Jones, S Petraki et al.
3 November 2022
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Introducing Lonza’s AAV suspension transient transfection platform to de-risk your path to clinic

Introducing Lonza’s AAV suspension transient transfection platform to de-risk your path to clinic

Suparna Sanyal
20 October 2022
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Expert Roundtable

Diagnostic & therapeutic uses for extracellular vesicles: insights into a rapidly evolving field

Diagnostic & therapeutic uses for extracellular vesicles: insights into a rapidly evolving field

S Wild, J Correia, A de Fougerolles et al.
30 November 2022
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FastFacts

Driving the viral vector expressway: speeding through AAV manufacturing

Driving the viral vector expressway: speeding through AAV manufacturing

Andi Ushijima, Henry George
17 November 2022
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Poster

Feeder free expansion of a clinically relevant number of human NK cells

Feeder free expansion of a clinically relevant number of human NK cells

Erica Heipertz
10 November 2022
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Automated & scalable closed-system platform for cell isolation and activation

Automated & scalable closed-system platform for cell isolation and activation

Hany Meås
3 November 2022
Read

Podcast

Shear ignorance? Think again: breaking the perception of shear within viral vector manufacturing

Shear ignorance? Think again: breaking the perception of shear within viral vector manufacturing

Ratish Krishnan, Akshat Gupta
10 November 2022
Listen
CAR-T cells: from cancer to autoimmunity

CAR-T cells: from cancer to autoimmunity

Dimitrios Mougiakakos
10 October 2022
Listen

Webinars