Vol 9 Issue 2

CELL AND GENE THERAPY INSIGHTS

Vol 9 Issue 2

Cell and Gene Therapy Insights Vol 9 Issue 2

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Featuring

Issue Spotlight: Cell Therapy Materials & Upstream Processing/Analytics
Cryopreservation & Cold Chain 2023
Other articles
Webinars

Cell Therapy Materials & Upstream Processing/Analytics

Expert Insight

Challenges in obtaining cellular therapy starting material for patients with sickle cell disease

Challenges in obtaining cellular therapy starting material for patients with sickle cell disease

Yvette C Tanhehco

Commentary

Overcoming challenges to CAR-T cell therapies in India

Overcoming challenges to CAR-T cell therapies in India

A Uppal, R Chakrabarti, N Chirmule et al.

FastFacts

Increase quality & standardization of cellular starting material

Increase quality & standardization of cellular starting material

Viewpoint

Distributed manufacturing models for ATMPs: can they work: do we understand the pitfalls?

Distributed manufacturing models for ATMPs: can they work: do we understand the pitfalls?

Interview

Ensuring success in working with apheresis centers

Ensuring success in working with apheresis centers

Bridging the knowledge gap in donor cellular starting material quality & variability

Bridging the knowledge gap in donor cellular starting material quality & variability

22 February 2023

Cryopreservation & Cold Chain 2023

Expert Insight

Taking lessons from nature to improve cell therapy cryopreservation

Taking lessons from nature to improve cell therapy cryopreservation

Jason Acker, Nishaka William, Mackenzie Coatham

FastFacts

Benefits of upstream seed train intensification & high-density cell banking

Benefits of upstream seed train intensification & high-density cell banking

Patrick Shu Miao

Journal articles

Innovator Insight

Implementing a closed cell therapy manufacturing process through strategic collaboration

Implementing a closed cell therapy manufacturing process through strategic collaboration

Øystein Åmellem, Xavier de Mollerat du Jeu, Brian Shy

FastFacts

Viral vector production guide: part 3. Standardizing the manufacturing process

Viral vector production guide: part 3. Standardizing the manufacturing process

Ultra-rapid microbial detection in cell & gene therapy products: the closest you can be to real-time release

Ultra-rapid microbial detection in cell & gene therapy products: the closest you can be to real-time release

Félix Montero-Julian

Exosome production process development in stirred-tank bioreactors

Exosome production process development in stirred-tank bioreactors

Stefan Schlößer

Reliable & scalable EuLV®️ stable LVV production system

Reliable & scalable EuLV®️ stable LVV production system

Infographic

mRNA manufacturing and analytics: INFOGRAPHIC

mRNA manufacturing and analytics: INFOGRAPHIC

Webinar Digest

Simplifying lentiviral downstream processing with a novel affinity resin & robust analytical tools

Simplifying lentiviral downstream processing with a novel affinity resin & robust analytical tools

Lentiviral titer determination: rapid & robust molecular methods suitable for validation

Lentiviral titer determination: rapid & robust molecular methods suitable for validation

Enhancing non-viral gene editing, processing, & expansion of T & NK cells

Enhancing non-viral gene editing, processing, & expansion of T & NK cells

Sung (Sung-Uk) Lee, Deepak Kumar

28 February 2023

Podcast

Challenges in cryogenic storage containers for cell & gene therapy

Challenges in cryogenic storage containers for cell & gene therapy

Interview

Establishing an end-to-end vector manufacturing solution for the gene therapy industry

Establishing an end-to-end vector manufacturing solution for the gene therapy industry

Pain points to potential: Positioning process and analytical development for next-gen cell therapies

Pain points to potential: Positioning process and analytical development for next-gen cell therapies

Sarah Campion, Alex Sargent

Improve your speed to therapy and drive efficiency by integrating supply chain and manufacturing

Improve your speed to therapy and drive efficiency by integrating supply chain and manufacturing

Robert Lutskus, Matthew Lakelin

Next-generation CRISPR mRNA-LNPs and scale up manufacturing for CAR T cells

Next-generation CRISPR mRNA-LNPs and scale up manufacturing for CAR T cells

Reka Geczy, Bernice Thommandru

Emerging trends and challenges in AAV manufacturing for gene therapies

Emerging trends and challenges in AAV manufacturing for gene therapies

M Fuller, A Eastham, I (John) Eugenis

Scale-up and deliver allogeneic cell therapies to large patient populations

Scale-up and deliver allogeneic cell therapies to large patient populations

M Langtry, K Panchalingam, I Friedrich Ben-Nun

Achieving reliable and scalable lentiviral vector production

Achieving reliable and scalable lentiviral vector production

Overcoming challenges to succeed when transitioning into a cGMP environment

Overcoming challenges to succeed when transitioning into a cGMP environment

Kris Wronski

Cell therapy manufacturing and 21 CFR Part 11 compliance: Overview and considerations for instrument software

Cell therapy manufacturing and 21 CFR Part 11 compliance: Overview and considerations for instrument software

Ashley Smith, Brianna Volk

Large-scale production of hiPSCs in automated bioreactors to produce wholly-cellular bioinks for tissue engineering

Large-scale production of hiPSCs in automated bioreactors to produce wholly-cellular bioinks for tissue engineering

Mark Skylar-Scott, Debbie Lee Lian Ho

Navigating bottlenecks in cell therapy manufacturing: A versatile and scalable platform solution

Navigating bottlenecks in cell therapy manufacturing: A versatile and scalable platform solution

Peter Yates