Vol 9 Issue 5

CELL AND GENE THERAPY INSIGHTS

June 2023 Issue

Vol 9 Issue 5

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Featuring

Issue Spotlight: Gene delivery platform evolution part 2: non-viral
Upstream processing 2023
Other articles
Webinars

SPOTLIGHT

Gene delivery platform evolution part 2: non-viral
Lynn Zechiedrich
Guest Editor:
Lynn Zechiedrich, Kyle & Josephine Morrow Chair & Professor in Molecular Virology & Microbiology at Baylor College of Medicine

Foreword

Gene delivery platform evolution part 2: non-viral—Foreword

Gene delivery platform evolution part 2: non-viral—Foreword

4 August 2023
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Expert Insight

The supporting role of plasmids in gene & cell therapy

The supporting role of plasmids in gene & cell therapy

Duarte Prazeres
5 July 2023
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FastFacts

Reducing risk for cell therapy manufacturing with a battle-tested electroporation platform

Reducing risk for cell therapy manufacturing with a battle-tested electroporation platform

Andrew Mancini
24 August 2023
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Addressing purification challenges: biological pipeline diversity and smaller manufacturing scales

Addressing purification challenges: biological pipeline diversity and smaller manufacturing scales

Sushma Nayak Teichert
11 July 2023
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Podcast

Non-viral methods for ex vivo cell & gene therapy: is the future non-viral?

Non-viral methods for ex vivo cell & gene therapy: is the future non-viral?

Valeria Annibaldi
31 July 2023
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Interview

Exploring current shortfalls and potential improvements for non-viral gene delivery in cystic fibrosis

Exploring current shortfalls and potential improvements for non-viral gene delivery in cystic fibrosis

Uta Griesenbach
4 August 2023
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Exploring the application of doggybone DNA to facilitate non-viral gene therapy delivery to hemophilia patients

Exploring the application of doggybone DNA to facilitate non-viral gene therapy delivery to hemophilia patients

Carol H Miao
19 July 2023
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Developing non-viral delivery & cell engineering technologies for ex vivo T cell immunotherapies

Developing non-viral delivery & cell engineering technologies for ex vivo T cell immunotherapies

Julie Shi, Nirveek Bhattacharjee
29 June 2023
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Expanding the potential of in vivo cell therapy with tLNP-RNAs (targeted lipid nanoparticle-RNA)

Expanding the potential of in vivo cell therapy with tLNP-RNAs (targeted lipid nanoparticle-RNA)

Adrian Bot
27 June 2023
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Vectors FOCUS

Upstream processing 2023

Research Article

Can novel bioreactors improve the cost of goods of viral vectors?

Can novel bioreactors improve the cost of goods of viral vectors?

Christos Stamatis, Alex Chatel, Suzanne Farid
19 June 2023
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Review

AAV production by transient transfection: strategies & challenges

AAV production by transient transfection: strategies & challenges

Amanda Bretti, Stephanie Doong
5 July 2023
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Innovator Insight

Environmental monitoring: optimizing microbial control in cell & gene therapy workflows

Environmental monitoring: optimizing microbial control in cell & gene therapy workflows

Nico Chow
19 June 2023
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FastFacts

A large-scale lentivirus manufacturing platform to accelerate time to clinic

A large-scale lentivirus manufacturing platform to accelerate time to clinic

Brian Mullan
2 June 2023
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Journal articles

Research Article

Validation of mRNA concentration determination by slope spectroscopy technology: a matrixed approach

Validation of mRNA concentration determination by slope spectroscopy technology: a matrixed approach

T Alvine, N Unsinn, J J Long et al.
13 June 2023
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Expert Insight

A guided demonstration of the Counting Method Evaluation Tool (COMET) for implementing the ISO 20391-2 Cell Counting standard

A guided demonstration of the Counting Method Evaluation Tool (COMET) for implementing the ISO 20391-2 Cell Counting standard

L Pierce, D Newton, S P Lund et al.
20 June 2023
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Innovator Insight

Analyzing full & empty AAV capsid ratio in less than 5 minutes

Analyzing full & empty AAV capsid ratio in less than 5 minutes

5 July 2023
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FastFacts

An optimized & streamlined approach for upstream & downstream lentiviral production

An optimized & streamlined approach for upstream & downstream lentiviral production

Gregory Piscitello, Paul Turiano
10 July 2023
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Efficient, scalable purification of VSV-G lentivirus by novel affinity chromatography

Efficient, scalable purification of VSV-G lentivirus by novel affinity chromatography

Frank Detmers
6 June 2023
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Podcast

Investing long-term in the cell & gene therapies of the future

Investing long-term in the cell & gene therapies of the future

Geeta Vemuri
28 March 2023
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Webinars