Vol 9 Issue 6

CELL AND GENE THERAPY INSIGHTS

July 2023 Issue

Vol 9 Issue 6

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Featuring

Issue Spotlight: Gene therapy CMC and analytics
Other articles
Webinars

SPOTLIGHT

Gene therapy CMC and analytics
Lauren Drouin
Guest Editor:
Lauren Drouin, Director, Analytical Development at Alexion, AstraZeneca Rare Disease

Foreword

Gene therapy CMC and analytics—Foreword

Gene therapy CMC and analytics—Foreword

2 August 2023
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Expert Insight

Optimizing ddPCR assay for characterizing AAV vector genome integrity

Optimizing ddPCR assay for characterizing AAV vector genome integrity

Aishwarya Shevade, John S Reeves, Andrew D Tustian
2 August 2023
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Regulatory perspective

Facing potential chemistry, manufacturing, & control (CMC) development challenges with recombinant adeno-associated viral vectors: available regulatory guidance & recommendations

Facing potential chemistry, manufacturing, & control (CMC) development challenges with recombinant adeno-associated viral vectors: available regulatory guidance & recommendations

Stuart Beattie
26 July 2023
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FastFacts

Technology transfer process excellence with an AAV comparability study

Technology transfer process excellence with an AAV comparability study

Isabel Guerrero Montero
1 September 2023
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Podcast

Interview: Navigating the complexities of biodistribution, transgene expression & vector shedding in gene therapy development

Interview: Navigating the complexities of biodistribution, transgene expression & vector shedding in gene therapy development

Paul Byrne
9 June 2023
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Interview

Identifying and leveraging viral vector critical quality attributes & critical process parameters using process analytical technologies

Identifying and leveraging viral vector critical quality attributes & critical process parameters using process analytical technologies

Jonathan Appleby, John Churchwell
23 August 2023
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Assessing the AAV analytic toolkit: considerations for application & regulatory compliance

Assessing the AAV analytic toolkit: considerations for application & regulatory compliance

Juliette Reviron
2 May 2023
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Journal articles

Innovator Insight

How can the gene therapy industry drive down the cost of goods to better serve patients?

How can the gene therapy industry drive down the cost of goods to better serve patients?

Emmanuelle Cameau
1 September 2023
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Development of anti-AAV assay for detection of pre-existing AAV immunity

Development of anti-AAV assay for detection of pre-existing AAV immunity

Zhe Liu
3 August 2023
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Navigating bottlenecks in cell therapy manufacturing: a versatile & scalable platform solution

Navigating bottlenecks in cell therapy manufacturing: a versatile & scalable platform solution

Peter Yates
27 July 2023
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Enabling instrument connectivity through digital automation

Enabling instrument connectivity through digital automation

Elizabeth Wahl
17 July 2023
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Scale-up and delivery of allogeneic cell therapies to large patient populations

Scale-up and delivery of allogeneic cell therapies to large patient populations

Marcos Langtry, Krishna Panchalingam, Inbar Friedrich Ben-Nun
14 July 2023
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Let the cells thrive: the next generation of cell expansion

Let the cells thrive: the next generation of cell expansion

Hugo Fabre, Maura Barbisin, Maria Knaub
28 June 2023
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Poster

Driving the expansion of mRNA into the therapeutic sphere

Driving the expansion of mRNA into the therapeutic sphere

12 July 2023
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Podcast

Modernizing cell therapy manufacturing to reduce vein-to-vein times

Modernizing cell therapy manufacturing to reduce vein-to-vein times

David Backer, Tony Ward
26 July 2023
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Webinars