Vol 9 Issue 11

CELL AND GENE THERAPY INSIGHTS

December 2023 Issue

Vol 9 Issue 11

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Featuring

Issue Spotlight: Clinical trends of 2023/ Tools of tomorrow
Characterizaton and Validation 2023
Other articles
Webinars

SPOTLIGHT

Clinical trends of 2023/ Tools of tomorrow

Expert Insight

A straightforward tool for developing a raw material supply strategy for cell & gene therapies

A straightforward tool for developing a raw material supply strategy for cell & gene therapies

K Kulenkampff, R Eigenmann, D Karlstetter et al.
8 January
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Expert Roundtable

Fast-tracking gene therapy breakthroughs: discussing the critical role of rapid testing

Fast-tracking gene therapy breakthroughs: discussing the critical role of rapid testing

R Legmann, G Thakur, S Levy et al.
5 January
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Viewpoint

Enabling cell culture technologies for the intensification & scale-up of viral vector manufacturing

Enabling cell culture technologies for the intensification & scale-up of viral vector manufacturing

Julien Robitaille
29 November 2023
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Key considerations for US biotechs setting up gene therapy studies in the UK and Europe

Key considerations for US biotechs setting up gene therapy studies in the UK and Europe

Chris Moore
14 November 2023
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Interview

Looking to a future of multiplex cell engineering

Looking to a future of multiplex cell engineering

Marco Alessandrini
11 January
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Exploring the burgeoning role of non-viral approaches in the delivery of nucleic acids

Exploring the burgeoning role of non-viral approaches in the delivery of nucleic acids

Zhenghong Gao
5 January
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Tracking current and predicting future cell therapy analytical toolkit evolution

Tracking current and predicting future cell therapy analytical toolkit evolution

Namyong Kim
22 November 2023
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Vectors FOCUS

Characterizaton and Validation 2023

Review

Profiling AAV vector heterogeneity & contaminants using next-generation sequencing methods

Profiling AAV vector heterogeneity & contaminants using next-generation sequencing methods

Ngoc Tam Tran, Phillip WL Tai
31 January
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Innovator Insight

Simplifying residual DNA quantitation and biotherapeutic manufacturing

Simplifying residual DNA quantitation and biotherapeutic manufacturing

Ilaria Scarfone
13 December 2023
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Webinar Digest

Regulatory considerations and validation strategies for mycoplasma testing for cell-based therapies

Regulatory considerations and validation strategies for mycoplasma testing for cell-based therapies

Michael Brewer
9 February
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Viewpoint

The current viral vector characterization landscape: from navigating evolving regulatory guidance to leveraging analytical tools for process development

The current viral vector characterization landscape: from navigating evolving regulatory guidance to leveraging analytical tools for process development

Ning Ding
8 December 2023
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Interview

Current limitations & potential innovations in developing IND-enabling rAAV- & lentivirus-based gene therapy drug products

Current limitations & potential innovations in developing IND-enabling rAAV- & lentivirus-based gene therapy drug products

Rahul Kaushik
6 December 2023
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Journal articles

Innovator Insight

Isolating CD4+ and CD8+ T cells for improved drug efficacy and increased productivity

Isolating CD4+ and CD8+ T cells for improved drug efficacy and increased productivity

Hany Meås
8 January
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Case study: becoming the first GMP-certified cell and gene therapy manufacturing facility in Thailand

Case study: becoming the first GMP-certified cell and gene therapy manufacturing facility in Thailand

Kitipong Uaesoontrachoon
5 January
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Achieving flexibility & scalability in cell therapy manufacturing through optimized cell isolation & activation

Achieving flexibility & scalability in cell therapy manufacturing through optimized cell isolation & activation

Eugene Kang
13 December 2023
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Expert Roundtable

Biological & operational considerations for iPSC-derived cell production

Biological & operational considerations for iPSC-derived cell production

A Mogen, A Fernandez-Perez, J Wang et al.
20 December 2023
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FastFacts

Is bigger better? Modeling AAV production to find optimization opportunities

Is bigger better? Modeling AAV production to find optimization opportunities

Andrea Vervoort
5 January
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The evolution of gene therapy manufacturing

The evolution of gene therapy manufacturing

Rachel Legmann
21 December 2023
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Unleashing the potential of mRNA therapeutics with high-quality bioreagents and optimized in vitro transcription

Unleashing the potential of mRNA therapeutics with high-quality bioreagents and optimized in vitro transcription

Jessica Madigan
20 December 2023
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Streamlining nucleic acid extraction for biotherapy manufacturing: manual and automated solutions for success

Streamlining nucleic acid extraction for biotherapy manufacturing: manual and automated solutions for success

Suzy Brown
30 November 2023
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Webinar Digest

Addressing regulatory guidance for HEK293 cells and AAV-based therapeutics manufacturing

Addressing regulatory guidance for HEK293 cells and AAV-based therapeutics manufacturing

Michael Brewer
15 December 2023
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Interview

US FDA Perspective: preparing for a bright and busy future for cell & gene therapy

US FDA Perspective: preparing for a bright and busy future for cell & gene therapy

Peter Marks
30 November 2023
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Creating pathways to necessary innovation in cell and gene therapy

Creating pathways to necessary innovation in cell and gene therapy

David Baltimore
17 November 2023
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Webinars