Vol 10 Issue 7

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Featuring

Issue Spotlight: Innovation in cellular immunotherapy: how to reach more patients?
Supply chain digitization 2024
Other articles
Webinars

Innovation in cellular immunotherapy: how to reach more patients?

Guest Editor:

Nina Bauer, Chief Business Officer at SmartCella

Foreword

Cellular immunotherapy: beyond hemalignancies

Nina Bauer

8 September

Read

Expert Insight

Patient-specific factors that could influence gene therapy outcomes in sickle cell disease

Abdulrahman Alsultan, Jaap Jan Boelens

1 September

Read

Innovator Insight

Enhancing CAR-T cell generation: optimizing non-viral engineering of resting T cells for improved cancer immunotherapy

Akshaya Chandrasekaran

11 September

Read

Regulatory perspective

Navigating the challenges of developing delivery devices for cell and gene therapy products in Europe

Eamonn McGowran, Patrick Ginty

26 August

Read

Viewpoint

Cellular immunotherapy—a matter of delivery?

Nina Bauer

4 September

Read

A pathway forward for CAR-NK cell therapy

Scott McComb

5 August

Read

Interview

Analyzing early successes, current challenges, and future opportunities in the in vivo cellular immunotherapy field

Ye Zeng

8 August

Read

Following the data: lessons learned from the development of afami-cel

Jo Brewer

5 August

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Addressing autoimmune diseases with engineered MSCs

Miguel Forte

13 June

Read

How will recent agency initiatives and likely future directions for regulatory CMC guidance impact the cellular immunotherapy space?

Adeyemi Afuwape

5 June

Read

Supply chain digitization 2024

Interview

Driving digital innovation for supply chain orchestration in cell and gene therapy

Christian Fuchs

27 August

Read

Streamlining cell and gene therapy supply chains: using semi-automation and AI for cost reduction

Stephan Kadauke

29 July

Read

Journal articles

Innovator Insight

iPSC-ing into the future of cell therapy: expansion in a hollow-fiber bioreactor

Molly Tregidgo, Nathan Frank

1 September

Read

Cryopreserving CAR-T cells in a novel rigid container maintains their phenotype and function compared to conventional cryobags and cryovials

D Pleitez, M Park, M Safford et al.

19 August

Read

Expert Roundtable

Unveiling the critical pathways in AAV potency evaluation and future trends in gene therapy

David Rangel, Guangping Gao, Nathalie Clement

8 August

Read

FastFacts

Navigating variability and scalability challenges in AAV production

Rafal Garus

4 September

Read

Accelerate gene therapy downstream process development using scalable pre-packed chromatography columns

Tim Schroeder

3 September

Read

STEMvision™ for CFU analysis of hematopoietic cell therapy products

Colin Hammond

27 August

Read

AAV capture purification scaling from bench to clinical manufacturing

Kathleen Mihlbachler

26 August

Read

Interview

Preparing for tomorrow’s cell and gene therapies today: lessons from 30 years in the field

Eric Faulkner

5 September

Read

Navigating the European landscape of advanced therapy funding and commercialization

Dmitry A Kuzmin

2 September

Read

Considerations to optimize and act upon long-term follow-up studies for cell and gene therapies

E Donahue, L Pelloso, D Takefman et al.

25 July

Read

Characterization and release testing for AAV therapies: empty/partial/full capsid analysis and impact on potency

K Doucette, F Vass, K Bertram

25 July

Watch

Developing off-the-shelf CAR-NK cells targeting CD70: updates from preclinical and early clinical studies

Sunil Acharya

1 August

Watch

Large-scale manufacturing of allogeneic stem cell-derived NK cell therapies

Monica Raimo, Jan Spanholtz

6 August

Watch

Understanding and leveraging cord blood bank capabilities and practices in cell therapy development

J Aho, A Conerty, S Shields et al.

15 August

Watch

Innovative approaches to lentiviral vector purification: achieving high yields and purity with a chromatography-free process

Nikki Votaw

20 August

Watch

Optimizing bioprocess purification: effective nucleic acid removal in high salt environments

Joanna Niska-Blakie, Eleonora Turco

22 August

Watch

Measuring key analytical attributes of viral vectors with macro mass photometry

Laura Pala

29 August

Watch

CELL AND GENE THERAPY INSIGHTS

August 2024 Issue

Vol 10 Issue 7

Featuring

SPOTLIGHT

Innovation in cellular immunotherapy: how to reach more patients?

Foreword

Cellular immunotherapy: beyond hemalignancies

Expert Insight

Patient-specific factors that could influence gene therapy outcomes in sickle cell disease

Innovator Insight

Enhancing CAR-T cell generation: optimizing non-viral engineering of resting T cells for improved cancer immunotherapy

Regulatory perspective

Navigating the challenges of developing delivery devices for cell and gene therapy products in Europe

Viewpoint

Cellular immunotherapy—a matter of delivery?

A pathway forward for CAR-NK cell therapy

Interview

Analyzing early successes, current challenges, and future opportunities in the in vivo cellular immunotherapy field

Following the data: lessons learned from the development of afami-cel

Addressing autoimmune diseases with engineered MSCs

How will recent agency initiatives and likely future directions for regulatory CMC guidance impact the cellular immunotherapy space?

Supply Chain FOCUS

Supply chain digitization 2024

Interview

Driving digital innovation for supply chain orchestration in cell and gene therapy

Streamlining cell and gene therapy supply chains: using semi-automation and AI for cost reduction

Journal articles

Innovator Insight

iPSC-ing into the future of cell therapy: expansion in a hollow-fiber bioreactor

Cryopreserving CAR-T cells in a novel rigid container maintains their phenotype and function compared to conventional cryobags and cryovials

Expert Roundtable

Unveiling the critical pathways in AAV potency evaluation and future trends in gene therapy

FastFacts

Navigating variability and scalability challenges in AAV production

Accelerate gene therapy downstream process development using scalable pre-packed chromatography columns

STEMvision™ for CFU analysis of hematopoietic cell therapy products

AAV capture purification scaling from bench to clinical manufacturing

Interview

Preparing for tomorrow’s cell and gene therapies today: lessons from 30 years in the field

Navigating the European landscape of advanced therapy funding and commercialization

Considerations to optimize and act upon long-term follow-up studies for cell and gene therapies

Webinars

Characterization and release testing for AAV therapies: empty/partial/full capsid analysis and impact on potency

Developing off-the-shelf CAR-NK cells targeting CD70: updates from preclinical and early clinical studies

﻿Large-scale manufacturing of allogeneic stem cell-derived NK cell therapies

Understanding and leveraging cord blood bank capabilities and practices in cell therapy development

Innovative approaches to lentiviral vector purification: achieving high yields and purity with a chromatography-free process

﻿﻿Optimizing bioprocess purification: effective nucleic acid removal in high salt environments

Measuring key analytical attributes of viral vectors with macro mass photometry

Large-scale manufacturing of allogeneic stem cell-derived NK cell therapies

Optimizing bioprocess purification: effective nucleic acid removal in high salt environments