Next-generation viral vector platforms for gene therapy, vaccine, and oncolytic virotherapy applications
Cell & Gene Therapy Insights 2021; 7(6), 681–685
10.18609/cgti.2021.097
Published: 21 June 2021
Viewpoint
Viral vectors play a critical role in several pioneering biotherapeutic approaches, including gene therapy, immuno-oncology, and vaccines. However, their immunogenicity means that most vector-based in vivo gene therapies are currently unsuitable both for systemic delivery and repeat dosing. Synthetic vector platforms can help overcome these challenges.