Let the cells thrive: the next generation of cell expansion

The cell therapy field has experienced tremendous growth in the number and variety of applications as well as disease targets under exploration for commercialization. At present, manufacturers face a wide range of decisions when it comes to implementing automated solutions in their processes. Committing to an unsuitable manufacturing technology early in development can result in expensive and unpredictable delays in late process transfers. Key steps in the cell therapy manufacturing process, such as cell expansion, can benefit from modular automation, allowing for easy integration into an established or growing manufacturing process. This article describes a cell expansion platform using hollow-fiber perfusion technology to provide an optimized cell culture environment for cell therapy manufacturing, from process development to clinical manufacturing.

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