Advancing AAV production scalability: enhancing purity, productivity, and yield
Cell & Gene Therapy Insights 2024; 10(2), 181–186
DOI: 10.18609/cgti.2024.026
Published: 19 March
Interview
Ashish Saksule
Abi Pinchbeck, Commissioning Editor, Cell & Gene Therapy Insights, speaks to Ashish Saksule, Principal Scientist, Vector Core Lead, Vertex Pharmaceuticals, about ongoing efforts to improve vector productivity and titer, addressing issues with the separation of empty and full capsids, and increasing scalability in the downstream enrichment of AAV.