Characterization and validation 2024

Implementing platform-based technologies to scale viral vector manufacturing consistently and efficiently

Cell & Gene Therapy Insights 2024; 10(11), 1597–1603

DOI: 10.18609/cgti.2024.183

Published: 19 December
Interview
Xueyuan Liu


Although advancements in viral vector manufacturing have enabled significant progress in cell and gene therapies, the field continues to face challenges in ensuring vector productivity and purity as manufacturing scales up. Abi Pinchbeck, Editor of BioInsights, speaks with Xueyuan Liu, Director of the Research Vector Core at Children’s Hospital of Philadelphia, about strategies for overcoming these challenges, including innovations in process optimization, vector design, and advanced analytical tools to enhance the clinical and commercial potential of viral vectors.