Worth the switch? Enhancing process performance for cell therapy manufacturing with an animal component-free raw material strategy

Cell & Gene Therapy Insights 2025; 11(1), 89–100

DOI: 10.18609/cgti.2025.011

Published: 3 March
Innovator Insight
Phil Morton, Shanya Jiang

Historically, cell therapies have relied heavily on animal- and human-derived components—but the variability associated with these sources can lead to inconsistency and safety concerns. In recent times, focus has shifted toward utilizing chemically-defined raw materials, including animal component-free proteins. This article explores the critical role raw materials play in process performance and highlights how animal component-free raw materials can enable optimized, reliable, and efficient cell therapy manufacturing.