Scale-up/scale-out of cell & gene therapy manufacturing

CELL AND GENE THERAPY INSIGHTS

September 2024

Scale-up/scale-out of cell & gene therapy manufacturing

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Expert Insight

The cell therapy industrial revolution: current successes, existing challenges, and expansion into new domains

The cell therapy industrial revolution: current successes, existing challenges, and expansion into new domains

Joel Gaston, Matthew Li

Innovator Insight

Mastering AAV production: best practices for small to large-scale manufacturing success and reduced development times

Mastering AAV production: best practices for small to large-scale manufacturing success and reduced development times

Emily Jackson-Holmes

Navigating cold chain complexity to enable clinical-to-commercial transition of advanced therapies

Navigating cold chain complexity to enable clinical-to-commercial transition of advanced therapies

Viewpoint

Decentralizing gene and cell therapy manufacturing: changing tides or uphill battle

Decentralizing gene and cell therapy manufacturing: changing tides or uphill battle

Interview

Shifting to non-viral in vivo therapies to enhance global patient access to genetic medicines

Shifting to non-viral in vivo therapies to enhance global patient access to genetic medicines

Leveraging the baculovirus-insect cell expression system for optimal AAV scale-up

Leveraging the baculovirus-insect cell expression system for optimal AAV scale-up

Barbara Sanders, Femke Hoeksema

Webinars

Extracellular vesicles: setting-up the path to IND with advanced characterization packages

Extracellular vesicles: setting-up the path to IND with advanced characterization packages

Davide Zocco

From the lab to the bench, scaling up regulatory T cell therapy

From the lab to the bench, scaling up regulatory T cell therapy

Megan K. Levings, Hany Meås

Clinical-scale non-viral gene edited CAR-NK cells for cell therapy

Clinical-scale non-viral gene edited CAR-NK cells for cell therapy

Krishanu Saha, Namritha Ravinder

Preparing for success in gene therapy purification

Preparing for success in gene therapy purification

X Fu, A Tustian, A Sharma et al.

Preparing for success in gene therapy analytical development

Preparing for success in gene therapy analytical development

Y Zhi, J Li, A Castillo

Automated cell isolation: flexibility meets performance

Automated cell isolation: flexibility meets performance

Enabling allogeneic cell therapy development: scaling up generation of PSC-derived NK cells

Enabling allogeneic cell therapy development: scaling up generation of PSC-derived NK cells

Mark Kennedy, Marcus Bunn

Unlocking success in CAR T tech transfer: from challenges to seamless execution

Unlocking success in CAR T tech transfer: from challenges to seamless execution

S Mills, N Blackburn, D Miskimin