BioInsights - Viral vector bioprocessing & analytics: tools and innovations to meet future demand - spotlight

CELL AND GENE THERAPY INSIGHTS

April 2020

Viral vector bioprocessing & analytics: tools and innovations to meet future demand

Download PDF

Expert Insight

Lentiviral vector manufacturing process enhancement utilizing TFDF<sup>™</sup> technology

Lentiviral vector manufacturing process enhancement utilizing TFDF^™ technology

T Williams, O Goodyear, L Davies et al.

Innovator Insight

Development and validation of quantitative real-time PCR for the detection of residual HEK-293 host cell DNA

Development and validation of quantitative real-time PCR for the detection of residual HEK-293 host cell DNA

Kara Norman

A reproducible, high-throughput platform to quantitatively study AAVs

A reproducible, high-throughput platform to quantitatively study AAVs

James White, Natalia Rodionova

Interview

Scaling AAV vector manufacture: overcoming roadblocks to the translation of gene therapies

Scaling AAV vector manufacture: overcoming roadblocks to the translation of gene therapies

Nicole Faust

Vector production in academia: obstacles and opportunities

Vector production in academia: obstacles and opportunities

Daniela Bischof, Emily Hopewell

Drawing parallels and cross-pollinating ideas between viral vector and vaccine fields

Drawing parallels and cross-pollinating ideas between viral vector and vaccine fields

Amine Kamen

What is ‘quality’ in viral vector manufacture? Strengths and limitations of current analytical tools

What is ‘quality’ in viral vector manufacture? Strengths and limitations of current analytical tools

Markus Hörer

How are fixed-bed bioreactors set to change viral vector processing?

How are fixed-bed bioreactors set to change viral vector processing?

P Velthof, P Puri, J Van Vliet

Are suspension-based systems for cell and gene therapy key to commercial-scale manufacture?

Are suspension-based systems for cell and gene therapy key to commercial-scale manufacture?

Patrick Erbacher

Webinars

Lentiviral vector process to accelerate cell and gene therapy clinical development and commercialization

Lentiviral vector process to accelerate cell and gene therapy clinical development and commercialization

Scaling up viral vector manufacturing with adherent and suspension cell cultures

Scaling up viral vector manufacturing with adherent and suspension cell cultures

C Glover, R Legmann, S Gupta

Advances in gene therapy delivery: next-generation transfection reagent for large-scale AAV manufacturing

Advances in gene therapy delivery: next-generation transfection reagent for large-scale AAV manufacturing

Mathieu Porte, Malik Hellal

Stable AAV producer cell lines: elevating vector manufacturing

Stable AAV producer cell lines: elevating vector manufacturing

Silke Wissing

AAV downstream processing for industrial scale production – moving towards commercial manufacturing

AAV downstream processing for industrial scale production – moving towards commercial manufacturing

Orjana Terova, Mikhail Goldfarb