Dec
9
2020
On demand

Streamlining CAR-T manufacture: reducing complexity and improving robustness through acoustic cell processing

Sponsor
Streamlining CAR-T manufacture: reducing complexity and improving robustness through acoustic cell processing

The large clinical pipeline under investigation worldwide highlights the continued advancement in CAR-T programs for both liquid cancers and solid tumors 

The importance of translating these successful trials to commercialization is clear. However, complexities in the manufacturing process challenge the industrialization of these therapies. In this webinar we examine how the application of one piece of process equipment across a range of unit operations can enable more robust, less complex, closed and automated CAR-T manufacturing. 

Attendees will benefit from:

  • An overview of current state of CAR-T manufacturing and the challenges of high complexity, high manipulation processes
  • Insights into manufacturing trends for closed and automated cell therapy processes, and best practices for industrialization of cell therapies
  • A greater understanding of the application of acoustic cell processing technology across CAR-T manufacturing unit operations
  • Understanding the benefits of the ekko™ system in supporting CAR-T programs from preclinical through commercialization
Kevin Lannon

Kevin Lannon

Associate Director, Business Development, Cell Therapy Processing, MilliporeSigma

Kevin Lannon is an Associate Director of Business Development for Cell Therapy Processing at MilliporeSigma. With a background in electrical and biomedical engineering, Kevin has focused on the implementation of novel automation platforms for biopharmaceuticals for over a decade. Kevin joined MillipreSigma through the acquisition of FloDesign Sonics in 2019 where he was the Director of Global Sales and supported the launch of the ekko™ acoustic cell processing platform. Prior to FloDesign Sonics, Kevin supported the launch of the ambr®15 platform from TAP Biosystems, working with early adopters to develop the ambr® family of products into the gold standard for mAb process development. After TAP was acquired by Sartorius Stedim, Kevin was a founding member of Sartorius’ Regenerative Medicine team, and drove growth into the emerging market of cell and gene therapies.

Benjamin Johnsrud

Benjamin Johnsrud

Technology Expert, Cell Therapy Processing, MilliporeSigma

Ben Ross-Johnsrud is a Technology Expert for Cell Therapy Processing at MilliporeSigma and came to the team through the recent acquisition of FloDesign Sonics, Inc. As part of his role, Ben leads customer engagement activities, demonstrating the capabilities of our acoustic cell processing technology, the ekko™. He is an expert in conceptualizing new manufacturing paradigms, using the full breadth of the acoustic technology and MiiliporeSigma cell therapy product portfolio to create solutions that meet the adapting process requirements and growing needs of commercial cell therapy supply. He initially joined FloDesign Sonics as an intern from Western New England University’s engineering program. Once he graduated with his Bachelor of Science in Engineering, he joined the company full time, and became a key developer of the acoustic technology that was to become the ekko. Ben also spearheaded some of the co-developments with industry heavyweights such as Merck and Co. and Pall, amongst others. Ben is a co-inventor on 17 patents to date, and he continues to be one of the most prolific product developers on the team, with a drive to expanding the MilliporeSigma product offering to power the next generation of cell therapies.

Matthew Li

Matthew Li

BioMedical Scientist & Engineer, Vor Bio

Matthew Li is Biomedical Scientist and Engineer with over 10 years of experience across an array of areas in the biotech field including CGT R&D and manufacturing, medical device development, and clinical research. He currently leads the Cell Therapy Manufacturing Innovation group at Vor Bio that engages across the CGT value chain interfacing with research, development, manufacturing, quality, regulatory, clinical, business development, and commercial to holistically address and solve challenges across numerous stages of development and production. Matthew holds a PhD in Medical Engineering and Medical Physics from the Massachusetts Institute of Technology.

Jordan Croteau

Jordan Croteau

formerly Principal Process Engineer in Process Development, Kite Pharma

Jordan Croteau has more than a decade of process automation and equipment design and implementation experience in biopharmaceutical process development, manufacturing, and operations. At Kite Pharma, Jordan was responsible for transforming the new technology introduction processes to ensure fitness for use in commercial manufacturing. Prior to Kite Pharma, he served as MES lead in the Global Automation Center of Excellence at Biogen, Inc. In this role, Jordan led the global execution system design and its integration with Biogen’s manufacturing and enterprise systems. Previously, Jordan worked as an automation integration consultant. He is currently a member of ISPE and ISA, and an active contributor to ISA 95. Jordan received a BS in Chemical Engineering from Worcester Polytechnic Institute.

SPEAKERS

Kevin Lannon
Kevin Lannon
Associate Director, Business Development, Cell Therapy Processing at MilliporeSigma
Benjamin Ross-Johnsrud
Benjamin Ross-Johnsrud
Technology Expert, Cell Therapy Processing at MilliporeSigma
Matthew Li
Matthew Li
BioMedical Scientist & Engineer at Vor Biopharma
Jordan Croteau
Jordan Croteau
formerly Principal Process Engineer in Process Development, Kite Pharma

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