Adeno-associated viral (AAV) vectors are the most prominent delivery vehicles being investigated for the treatment of genetic diseases. Although the successes of AAV-based gene therapies in pre-clinical and clinical studies are encouraging, limitations in vector characterization and manufacturing still pose significant challenges.
Here, a panel of experts in vector development and characterization will discuss the emerging trends and future challenges of AAV-based gene therapies. The panel will then dive deeper into analytical methods used to characterize vector critical quality attributes (CQAs) and highlight crucial areas for improvement in AAV manufacturing.
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