Purification of neuronal subpopulations is crucial to the investigation of cell pathology in neurodegenerative diseases. Cultures obtained from brain tissue usually contain multiple different primary neurons, interneurons, and glial cells, making it difficult to identify cell type-specific effects. Cell sorting-based cell-culture methods could therefore be used to purify neuronal populations, opening research opportunities in the field of neurodegenerative diseases.
This webinar explores how cell sorting-based culture methods can be used for the enrichment of neuronal subpopulations, with the example of sorting direct and indirect pathway striatal medium spiny projection neurons for the analysis of Parkinson's disease.
Attend this webinar to learn how to: