Ex vivo engineering of hematopoietic stem cells using RNA-LNPs for cell and gene therapies
Jul
2
2024
Upcoming webinar

Ex vivo engineering of hematopoietic stem cells using RNA-LNPs for cell and gene therapies

Tuesday 08:00 PDT / 11:00 EDT / 16:00 BST / 17:00 CEST
Sponsor
Ex vivo engineering of hematopoietic stem cells using RNA-LNPs for cell and gene therapies

Delivering nucleic acids using lipid nanoparticles (LNP) to target cells has tremendous potential to enable new cell and gene therapies. In this webinar, we'll share insights on an innovative genomic medicines toolkit, focusing on technologies that streamline the development of RNA-LNP medicines.

We're excited to introduce you to off-the-shelf reagents designed specifically for producing RNA-LNPs optimized for hematopoietic stem cells (HSC), alongside the NanoAssemblr™ manufacturing platform equipped with NxGen™ technology. This platform can enable rapid development and scale-up production of RNA-LNPs. Through this presentation, we will walk you through data for ex vivo hematopoietic stem cell therapies showcasing how LNPs serve as a vehicle for RNA delivery for the transient expression of therapeutic genes and gene-editing nucleases.

Join us in this webinar to learn more about:

  • How RNA-LNPs are being used to develop the next-generation of HSC therapies
  • How to perform highly efficient gene editing in CD34+ HSCs
  • Seamless integration of LNPs in CD34+ HSC cell manufacturing workflow
  • Scaling up ex vivo cell therapy from discovery to preclinical using the NanoAssemblr™ LNP manufacturing platform
Reka Geczy
Reka Geczy
Associate Senior Scientist, Product Development at Cytiva

Reka is a Senior Scientist at Cytiva and is part of the team developing lipid nanoparticle reagents, such the T Cell Kit for mRNA and the recently launched CD34+ HSC LNP kits. Currently, her team is continuing the R&D of efficient lipid nanoparticle compositions for achieving the next generation of cell and gene therapies. Prior to her role at Cytiva, Reka got a PhD in Pharmaceutical Sciences from the University of British Columbia with high impact publications at the interface of microfluidics and drug delivery.