Improving cell therapy manufacturing with on-line monitoring of critical process parameters during cell expansion

Live30 webinars are thirty-minute presentations designed to update you on the latest innovations, applications, and data in a fast yet interactive format.

Automated manufacturing systems offer significant benefits to cell therapy manufacturing, such as reducing manual intervention, improving consistency, and lowering overall costs. However, fully transitioning from manual protocols to automated processing necessitates the integration of real-time process parameters in development and cGMP manufacturing.

Glucose and lactate concentrations can serve as leading indicators of the health and growth kinetics of cells. When considered alongside the perfusion rate, these metabolic indicators can help optimize media usage and determine the optimal harvest time. The synergy between automated cell expansion systems like Quantum Flex and MAVEN helps enhance process understanding and facilitates dynamic adjustments to process conditions.

This webinar will explore how automated monitoring and control of glucose and lactate levels can significantly improve the cell therapy process.

• Explore methodologies to achieve greater robustness and lower cost of goods in cell therapy manufacturing
• Understand the benefits and considerations in real-time monitoring of key process parameters such as glucose and lactate
• Learn how to enable the creation and maintenance of optimal cell expansion conditions

Boris Aleynik

Director of Strategy and Product Marketing at 908 Devices

Boris Aleynik is a Director of Strategy and Product Marketing at 908 Devices (Boston, MA) where he leads development and implementation of marketing strategies for Life Science products. Prior to this, Boris was a Director of Strategic Product Planning for Industry 4.0 Technologies at Pall Life Sciences. Boris received his MBA from Northwestern University in 2015 and BS in Mechanical Engineering from Iowa State University in 2007.

Mindy Miller

Lead Research Scientist at Terumo Blood and Cell Technologies

Dr Mindy Miller is a Senior Scientist/Manager at Terumo Blood and Cell Technologies (Lakewood, CO) where she leads a team in the development of innovative solutions for cell therapies. Mindy holds a doctorate in Immunology from the University of Missouri and conducted post-doctoral studies at the University of Missouri, as well as National Jewish Health in Denver, CO. She has authored multiple scientific publications and is the recipient of the Young Investigator Award from the American Association of Immunologists.

Watch now

SPEAKERS

Boris Aleynik

Director of Strategy and Product Marketing at 908 Devices

Mindy Miller

Lead Research Scientist at Terumo Blood and Cell Technologies

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