Supply chain challenges and issues facing the autologous cell manufacturing industry

Published: 24 April 2020
Expert Insight
Kan Wang,
Kan Wang
Research Engineer II at Georgia Institute of Technology
Ben Wang,
Ben Wang
Executive Director, Georgia Tech Manufacturing Institute at Georgia Institute of Technology
Chip White
Chip White
Professor, Schneider National Chair in Transportation & Logistics, H. Milton Stewart School of Industrial & Systems Engineering at Georgia Institute of Technology

We discuss three supply chain challenges and issues facing the autologous cell manufacturing industry that may impact patient outcome and supply chain performance in a commercial setting. These are (i) the potential value of giving priority to the sickest patients with respect to the start of manufacturing their therapy, (ii) determining the optimal manufacturing capacity and reagent replenishment policy for a single cell manufacturing facility, given demand forecasts and patient service levels, and (iii) the resilience of reconfigurable supply chain networks for supply chains with geographically distributed manufacturing capacity.

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