Automated plasmid assembly: a perspective from early drug discovery

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Operations strategy for a scalable CGT supply chain: key CXO insights

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Revolutionizing the treatment of cancer with allogeneic CAR-T cell therapy

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Enhancing AAV process quality and efficiency: three case studies highlighting the benefits of upgraded analytics on downstream process development

E Hudspeth, I Green, T Dewosky et al

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Analytics for cell and gene therapy products in early development: points to consider before preparing an IND for a first-in-human clinical trial

William E Janssen, Scott Burger

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The cell therapy industrial revolution: current successes, existing challenges, and expansion into new domains

Joel Gaston, Matthew Li

24 September 2024

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Upstream processing of viral vectors: a summary

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The sweet cell of success: key considerations for the sourcing and production of pluripotent cell lines for therapeutic development

Samuel JI Blackford, Nathan C Manley

21 May 2024

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Raw materials and supplies for cell therapies: end to end expectations and best practices

Lili Belcastro

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A straightforward tool for developing a raw material supply strategy for cell & gene therapies

K Kulenkampff, R Eigenmann, D Karlstetter et al

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Considerations for development of gene-edited PSC-based therapies

Brent Morse, Amanda Mack

14 November 2023

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Optimizing ddPCR assay for characterizing AAV vector genome integrity

Aishwarya Shevade, John S Reeves, Andrew D Tustian

03 August 2023

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The supporting role of plasmids in gene & cell therapy

Duarte Prazeres

06 July 2023

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A guided demonstration of the Counting Method Evaluation Tool (COMET) for implementing the ISO 20391-2 Cell Counting standard

L Pierce, D Newton, S P Lund et al

21 June 2023

Expert Insight

Challenges in obtaining cellular therapy starting material for patients with sickle cell disease

Yvette C Tanhehco

22 March 2023

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Taking lessons from nature to improve cell therapy cryopreservation

Jason Acker, Nishaka William, Mackenzie Coatham

20 March 2023

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Exosomes: next generation vectors for drug delivery & gene therapy

Jess Morhayim, Jeroen de Vrij

12 December 2022

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Harnessing the power of design of experiments for cell therapy research & process development

Sean O’Farrell

30 November 2022

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Expanding the analytical toolbox to address complex cell-based therapies

Nathan C Manley, Samuel JI Blackford

18 November 2022

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Strategic partnering to enable cell therapy commercialization

02 October 2022

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Stabilizing DNA–PEI complexes improves scalability of suspension lentiviral viral vector and AAV processes

B Olden, H Seo, R Barnes et al

28 August 2022

Expert Insight