Addressing challenges in AAV manufacturing scale-up for cost-effective gene therapies

Andrew D Tustian

06 March 2025

Interview

Implementing platform-based technologies to scale viral vector manufacturing consistently and efficiently

Xueyuan Liu

19 December 2024

Interview

Navigating the complexities of AAV and lentiviral vector characterization

Susumu Uchiyama

12 December 2024

Interview

History and progress in viral vector particle size distribution analysis

Steven Berkowitz

09 December 2024

Interview

Process optimization for AAV-based gene therapy: insights on downstream purification

Srivatsan Ramesh

17 October 2024

Interview

Shifting to non-viral in vivo therapies to enhance global patient access to genetic medicines

Hari Pujar

27 September 2024

Interview

Leveraging the baculovirus-insect cell expression system for optimal AAV scale-up

Barbara Sanders, Femke Hoeksema

19 September 2024

Interview

Exploring analytical assays and CMC challenges for viral vector-based therapies

Vladimir Slepushkin

19 June 2024

Interview

Advancing the analytical toolkit to drive viral gene delivery

Chelsea Amstuz, Itzcoatl Pla

18 June 2024

Interview

Navigating gene therapy QC: exploring the expanding AAV vector analytical toolkit

Van Hoang

12 June 2024

Interview

Revolutionizing AAV manufacturing: innovations in process and capsid development

Michael DiBiasio-White

03 June 2024

Interview

Developing focused ultrasound as a novel gene delivery tool to overcome the blood–brain barrier

Rikke Hahn Kofoed

29 May 2024

Interview

Advancing capsid engineering: improving tropism and delivery efficiency of AAV

Li Ou

26 March 2024

Interview

Achieving scalability: strategic insights into avoiding the pitfalls of the cell and gene therapy supply chain

Donna Rill

19 March 2024

Interview

Advancing AAV production scalability: enhancing purity, productivity, and yield

Ashish Saksule

19 March 2024

Interview

Quantitative viral vector characterization: prioritizing genome vector integrity

David Dobnik

21 February 2024

Interview

Exploring the burgeoning role of non-viral approaches in the delivery of nucleic acids

Zhenghong Gao

05 January 2024

Interview

Current limitations & potential innovations in developing IND-enabling rAAV- & lentivirus-based gene therapy drug products

Rahul Kaushik

06 December 2023

Interview

Developing a multiplex gene editing approach targeting viral infection

TJ Cradick

08 November 2023

Interview

Building with the patient in mind: designing a state-of-the-art facility for viral vector manufacturing

Louis-Marie De Montgrand, Morad El Gueddari

11 October 2023

Interview

Navigating lentiviral vector downstream bioprocessing: an engineering perspective

Andrea Rayat

05 October 2023

Interview