CELL AND GENE THERAPY INSIGHTS

February 2025 Issue

Volume 11 Issue 1

Cell and Gene Therapy Insights Volume 11 Issue 1

Featuring

Issue Spotlight: Expanding cellular immunotherapy
Vectors focus: Manufacturing Scale-up 2025
Other articles
Webinars

SPOTLIGHT

Expanding cellular immunotherapy
David Morrow
Guest Editor:
David Morrow, Scientific Programme Manager, Translational Medicine & Drug Development at EATRIS

Foreword

Breaking barriers in cell and gene therapy: advancing ATMPs through innovation and collaboration

Breaking barriers in cell and gene therapy: advancing ATMPs through innovation and collaboration

A Ussi, A Andreu, F Bietrix et al.
28 February
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Innovator Insight

Worth the switch? Enhancing process performance for cell therapy manufacturing with an animal component-free raw material strategy

Worth the switch? Enhancing process performance for cell therapy manufacturing with an animal component-free raw material strategy

Phil Morton, Shanya Jiang
3 March
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Commentary

CAR-T cells in B-cell mediated autoimmune diseases: do all roads lead to Rome?

CAR-T cells in B-cell mediated autoimmune diseases: do all roads lead to Rome?

Dimitrios Mougiakakos
13 February
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Viewpoint

Efficient non-viral engineering of immune cells for cell therapy using circular single-stranded DNA

Efficient non-viral engineering of immune cells for cell therapy using circular single-stranded DNA

Hao Wu
13 January
Read

Interview

Solid tumor treatment: how can we achieve therapy efficacy and persistence in the next frontier of cell therapies?

Solid tumor treatment: how can we achieve therapy efficacy and persistence in the next frontier of cell therapies?

Sebastian Kobold
23 January
Read

Vectors FOCUS

Manufacturing Scale-up 2025

Interview

Addressing challenges in AAV manufacturing scale-up for cost-effective gene therapies

Addressing challenges in AAV manufacturing scale-up for cost-effective gene therapies

Andrew D Tustian
6 March
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Journal articles

Innovator Insight

Enabling allogeneic cell therapy development: scaling up generation of PSC-derived NK cells

Enabling allogeneic cell therapy development: scaling up generation of PSC-derived NK cells

Mark Kennedy, Marcus Bunn
10 March
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Maximizing CAR-T cell yields: scalable solutions with perfusion and stirred-tank bioreactors

Maximizing CAR-T cell yields: scalable solutions with perfusion and stirred-tank bioreactors

J Hengst, Q Rafiq, R Ladi et al.
27 February
Read
Maximizing cell therapy process flexibility and efficiency with next-generation technologies

Maximizing cell therapy process flexibility and efficiency with next-generation technologies

19 February
Read
Speeding to success: accelerating cell therapy development and manufacturing workflows

Speeding to success: accelerating cell therapy development and manufacturing workflows

17 February
Read
Toward clinical-scale nonviral gene-edited CAR-NK cells for cell therapy

Toward clinical-scale nonviral gene-edited CAR-NK cells for cell therapy

Namritha Ravinder, Krishanu Saha
13 February
Read
Make more lentivirus and make it right the first time

Make more lentivirus and make it right the first time

Katherine Schewe
10 February
Read
Enhancing CAR-T therapy development: harnessing cell selection flexibility

Enhancing CAR-T therapy development: harnessing cell selection flexibility

Tamara Laskowski, Nuala Trainor
6 February
Read
Optimizing for the future: streamlining the production of T cell-based immunotherapies

Optimizing for the future: streamlining the production of T cell-based immunotherapies

Soong Poh Loong, Paula Lam
28 January
Read

Expert Roundtable

Why peer review matters: insights from the scientific community

Why peer review matters: insights from the scientific community

A Goyal, A Cockroft, P Theocharous et al.
28 February
Read

Webinar Digest

Control your AAV titers with in-line UV-Vis analysis and PAT-driven UF/DF systems

Control your AAV titers with in-line UV-Vis analysis and PAT-driven UF/DF systems

Brandon Goldberg
3 February
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Poster

INTERACTIVE EVENT SUMMARY: Harnessing flow cytometry for high-throughput screening in immunotherapy development

INTERACTIVE EVENT SUMMARY: Harnessing flow cytometry for high-throughput screening in immunotherapy development

20 January
Read

Interview

Regulatory innovations: why is the UK an attractive hub for CGT development?

Regulatory innovations: why is the UK an attractive hub for CGT development?

Rehma Chandaria
13 February
Read
Driving innovation in cell and gene therapy: the role of AI and robotics

Driving innovation in cell and gene therapy: the role of AI and robotics

Kenneth Harris, Mitchel Sivilotti, Anthony Rotunno
27 January
Read

Conference Insight

The Nordics are dancing on

The Nordics are dancing on

Helena Strigard
23 January
Read

Forecast

New frontiers for cell and gene therapy: addressing 2024 milestones and the outlook for 2025

New frontiers for cell and gene therapy: addressing 2024 milestones and the outlook for 2025

A Bersenev, F Salmon, J Dowd et al.
5 March
Read

Webinars