Achieving high-titer rAAV production with significantly reduced encapsidated host cell DNA

Ines Goncalves

10 April 2025

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Moving AAV gene therapy beyond rare disease to address large patient populations with chronic disease

Dan Oliver, Ji Hyun Lee

09 April 2025

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Transforming viral vector manufacturing with next-generation CGMP plasmids platform

John Bowen, Brian Tomkowicz

02 April 2025

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Cost reduction of viral vector processes using 3D nanofiber-based cell culture systems in upstream bioprocessing

Rob Noel, Geddy Hamblen, Christel Fenge

01 April 2025

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Salt-tolerant endonucleases, the benefits for viral vector manufacturing and a comparison of two marketed enzymes

Marc Struhalla, Svenja Michalek

26 March 2025

Innovator Insight

Efficient AAV purification: resin reuse and scalable polish method

Nicolas Laroudie, Duncan Dulac

25 March 2025

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Industrialization of AAV manufacturing with Xcite® transient and stable production platforms

Suparna Sanyal, Peng Wang

19 March 2025

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Addressing challenges in AAV manufacturing scale-up for cost-effective gene therapies

Andrew D Tustian

06 March 2025

Interview

AAV capsid analysis and quantification with chromatography and ultracentrifugation-based techniques

Andreja Livk, Sebastijan Peljhan

27 February 2025

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Avoiding scale-up pitfalls: upstream process development strategies for AAV manufacturing

Sandy Tseng, Hugh Murray

26 February 2025

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Achieving robust and scalable AAV empty/full capsid separation for gene therapy

Julio Huato, Mark Schofield

26 February 2025

Innovator Insight

Modernizing viral clearance study strategy: regulatory updates and industry best practices

Audrey Chang, Kathleen Kenney

25 February 2025

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Make more lentivirus and make it right the first time

Katherine Schewe

10 February 2025

Innovator Insight

Advancing AAV manufacturing: strategic insights and cost-effective solutions for the future of gene therapies

Michael DiBiasio-White, Ying Cai, Roland Pach

06 February 2025

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Control your AAV titers with in-line UV-Vis analysis and PAT-driven UF/DF systems

Brandon Goldberg

03 February 2025

Webinar Digest

Precision in production: optimizing monitoring and quality control for high-value plasmids

Oleksandr Karpenko

03 February 2025

Webinar Digest

Big pharma case study: alpha testing of a generic anti-AAV kit and comparison to in-house methods

Kira Hedström, Eva-Maria Thüring

30 January 2025

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Efficient non-viral engineering of immune cells for cell therapy using circular single-stranded DNA

Hao Wu

13 January 2025

Viewpoint

Implementing platform-based technologies to scale viral vector manufacturing consistently and efficiently

Xueyuan Liu

19 December 2024

Interview

Demystifying AAV affinity capture: mapping AAV affinity ligand footprints with cryo-electron microscopy

Nathaniel Clark

13 December 2024

Webinar Digest

Navigating the complexities of AAV and lentiviral vector characterization

Susumu Uchiyama

12 December 2024

Interview