Vol 8 Issue 3

CELL AND GENE THERAPY INSIGHTS

April 2022 Issue

Vol 8 Issue 3

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Featuring

Issue Spotlight: Vector bioprocessing
Best practices for ensuring cell and gene therapy supply chain scalability 2022
Other articles
Webinars

SPOTLIGHT

Vector bioprocessing

Foreword

Vector bioprocessing spotlight

Vector bioprocessing spotlight

Franz Gerner
1 May 2022
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Research Article

Clarification of recombinant adeno-associated virus (rAAV) & lentivirus from adherent culture

Clarification of recombinant adeno-associated virus (rAAV) & lentivirus from adherent culture

Rajeshwar Chinnawar, Nicholas Marchand
30 April 2022
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Expert Insight

Adeno-associated virus process development: optimization & development of a scalable elution for polishing chromatography

Adeno-associated virus process development: optimization & development of a scalable elution for polishing chromatography

Daniel Martin
10 April 2022
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Adeno-associated viral vector process development challenges in early research & preclinical study

Adeno-associated viral vector process development challenges in early research & preclinical study

Ashish Saksule
27 March 2022
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Innovator Insight

From cells to purified capsids: How to develop a scalable rAAV process

From cells to purified capsids: How to develop a scalable rAAV process

Åsa Hagner McWhirter
13 June 2022
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Process development innovations to improve gene therapy manufacturing

Process development innovations to improve gene therapy manufacturing

Jessica Hilmoe, Michael Shen
7 June 2022
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Accelerating cell & gene therapy workflows with next-generation analytical tools

Accelerating cell & gene therapy workflows with next-generation analytical tools

Chris Heger
21 April 2022
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Flexible & scalable solutions for AAV viral vector production using a templated platform

Flexible & scalable solutions for AAV viral vector production using a templated platform

Eva Fong
17 April 2022
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Expert Roundtable Video

Thinking big: the need for innovation in the production of lentivirus-based cell and gene therapies

Thinking big: the need for innovation in the production of lentivirus-based cell and gene therapies

H Leinonen, J Moscariello, L Davies et al.
19 April 2022
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FastFacts

POROS CaptureSelect AAVX Wash Optimization Study for Optimized Recovery and Purity of AAV6 Capsids

POROS CaptureSelect AAVX Wash Optimization Study for Optimized Recovery and Purity of AAV6 Capsids

31 May 2022
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Detecting residual host cell DNA with Droplet Digital PCR technology

Detecting residual host cell DNA with Droplet Digital PCR technology

Mark White
3 April 2022
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Poster

Manufacturing of RCA-free adenoviral vectors

Manufacturing of RCA-free adenoviral vectors

Nico Scheer
27 March 2022
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Viewpoint

Future trends in viral vector process & product development

Future trends in viral vector process & product development

Ramji Krishnan
27 April 2022
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Considerations for demonstrating comparability of AAV processes

Considerations for demonstrating comparability of AAV processes

Laura Giersch
25 April 2022
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Interview

Exploring commercial upstream processing of AAV

Exploring commercial upstream processing of AAV

Hugo Rojas
27 March 2022
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Supply Chain FOCUS

Best practices for ensuring cell and gene therapy supply chain scalability 2022

FastFacts

Key factors in cell cryopreservation and impact on manufacturability of cell and gene therapies

Key factors in cell cryopreservation and impact on manufacturability of cell and gene therapies

Robert Newman, PhD
11 April 2022
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Poster

Supply chain efficiency and sourcing for scaling your gene therapy operation

Supply chain efficiency and sourcing for scaling your gene therapy operation

Céline Martin, Don Young
2 May 2022
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Podcast

Precisely for CGT: automating aseptic filling for lowest volumes

Precisely for CGT: automating aseptic filling for lowest volumes

Barbara Fischer
27 March 2022
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Interview

A collaborative approach to cell & gene therapy supply chain management

A collaborative approach to cell & gene therapy supply chain management

Anthony Johnson
23 April 2022
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Journal articles

Editorial

Unproven stem cell-based interventions & harm to existing & future patients

Unproven stem cell-based interventions & harm to existing & future patients

Flora Naylor, Kirstin RW Matthews
27 March 2022
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Innovator Insight

The digital revolution: technological innovations to enable automation in cell therapy manufacturing

The digital revolution: technological innovations to enable automation in cell therapy manufacturing

Sean Chang, Bruce Greenwald, Krishnendu Roy
11 April 2022
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FastFacts

Laying the foundations for success with scale-down models

Laying the foundations for success with scale-down models

14 April 2022
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Reducing processing risks & operational challenges for low volume fluid transfer

Reducing processing risks & operational challenges for low volume fluid transfer

Troy Ostreng, Jayanthi Grebin
28 March 2022
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EBook

Ebook: Viral Vector Purification

Ebook: Viral Vector Purification

27 March 2022
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Webinar Digest

Rapid translation of a cellular therapeutic from research to clinic

Rapid translation of a cellular therapeutic from research to clinic

Ashish Patel, Joseph Candiello
1 May 2022
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Regulatory Insight

Current global regulatory landscape for biodistribution & shedding assessment of rAAV gene therapies & recommendations of the IMI ARDAT consortium on future directions

Current global regulatory landscape for biodistribution & shedding assessment of rAAV gene therapies & recommendations of the IMI ARDAT consortium on future directions

N Anne Schmidt, J Giblin, T K MacLachlan et al.
24 April 2022
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Webinars